Polymeric micelles in cancer therapy: State of the art

B Ghosh, S Biswas - Journal of Controlled Release, 2021 - Elsevier
In recent years, polymeric micelles have been extensively utilized in pre-clinical studies for
delivering poorly soluble chemotherapeutic agents in cancer. Polymeric micelles are formed …

Polymeric micelles as drug delivery vehicles

Z Ahmad, A Shah, M Siddiq, HB Kraatz - Rsc Advances, 2014 - pubs.rsc.org
Though much progress has been made in drug delivery systems, the design of a suitable
carrier for the delivery of hydrophobic drugs is still a major challenge for researchers. The …

Biomedical applications of biodegradable polymers

BD Ulery, LS Nair, CT Laurencin - Journal of polymer science …, 2011 - Wiley Online Library
Utilization of polymers as biomaterials has greatly impacted the advancement of modern
medicine. Specifically, polymeric biomaterials that are biodegradable provide the significant …

Multifunctional polymeric micelles for delivery of drugs and siRNA

AM Jhaveri, VP Torchilin - Frontiers in pharmacology, 2014 - frontiersin.org
Polymeric micelles, self-assembling nano-constructs of amphiphilic copolymers with a core-
shell structure have been used as versatile carriers for delivery of drugs as well as nucleic …

Recent progress in biomedical applications of Pluronic (PF127): Pharmaceutical perspectives

MSH Akash, K Rehman - Journal of Controlled Release, 2015 - Elsevier
Most of the administered anti-cancer drugs are hydrophobic in nature and are known to
have poor water solubility, short residence time, rapid clearance from the body and systemic …

Nanodrug delivery in reversing multidrug resistance in cancer cells

S Kapse-Mistry, T Govender, R Srivastava… - Frontiers in …, 2014 - frontiersin.org
Different mechanisms in cancer cells become resistant to one or more chemotherapeutics is
known as multidrug resistance (MDR) which hinders chemotherapy efficacy. Potential …

Multifunctional Pluronic P123/F127 mixed polymeric micelles loaded with paclitaxel for the treatment of multidrug resistant tumors

W Zhang, Y Shi, Y Chen, J Ye, X Sha, X Fang - Biomaterials, 2011 - Elsevier
The aim of this study was to exploit the possibility of combination of active targeting function
of folic acid by folate receptor-mediated endocytosis and overcoming multidrug resistance …

Nanoparticle delivery systems for cancer therapy: advances in clinical and preclinical research

SP Egusquiaguirre, M Igartua, RM Hernández… - Clinical and …, 2012 - Springer
Conventional anticancer drugs display significant shortcomings which limit their use in
cancer therapy. For this reason, important progress has been achieved in the field of …

Hyaluronic acid-coated liposomes for targeted delivery of paclitaxel, in-vitro characterization and in-vivo evaluation

F Ravar, E Saadat, M Gholami… - Journal of controlled …, 2016 - Elsevier
Breast cancer is the leading cause of cancer death in women. Chemotherapy is regarded as
the most essential strategy in inhibiting the proliferation of tumor cells. Paclitaxel is a widely …

Theranostic vitamin E TPGS micelles of transferrin conjugation for targeted co-delivery of docetaxel and ultra bright gold nanoclusters

MS Muthu, RV Kutty, Z Luo, J Xie, SS Feng - Biomaterials, 2015 - Elsevier
The aim of this work was to develop an advanced theranostic micelles of D-alpha-tocopheryl
polyethylene glycol 1000 succinate (TPGS), which are conjugated with transferrin for …