The highly reactive dicarbonyl methylglyoxal (MGO) is mainly formed as byproduct of
glycolysis. Therefore, high blood glucose levels determine increased MGO accumulation …

Vascular dysfunction plays a pivotal role in the development of systemic complications
associated with arterial hypertension and diabetes. The endothelium, or more specifically …

Methylglyoxal (MGO)-induced cellular apoptosis, oxidative stress, inflammation, and AGE
formation are specific events that induce vascular endothelial cell (EC) toxicity in endothelial …

Nitric oxide (NO) is an important vasodilator produced by vascular endothelium. Its
enzymatic formation is derived from three different synthases: neuronal (nNOS), endothelial …

This article reviews recent nutritional approaches for counteracting the development of
pulmonary hypertension syndrome (PHS; ascites) in broiler chickens especially when they …

Background and aims Plenty of literature has documented that fine particulate matter (PM
2.5) exposure is related to blood pressure (BP) elevation. Vascular dysfunction is the …

The lymphatic system is involved in the pathogenesis of edema, inflammation, and cancer
metastasis. Because lymph vessels control fluid electrolytes and volume balance, changes …

Impaired angiogenesis leads to long-term complications and is a major contributor of the
high morbidity in patients with Diabetes Mellitus (DM). Methylglyoxal (MGO) is a glycolysis …

Eukaryotic elongation factor 2 kinase (eEF2K) is a Ca2+/calmodulin-dependent protein
kinase. We recently demonstrated that eEF2K protein increases in mesenteric artery from …

Background Hypertension is a serious component of metabolic syndrome (MetS).
Hypothesis This research investigates the potential protective effect of limonin against MetS …