The neuroprotective effects of thymoquinone: a review

T Farkhondeh, S Samarghandian… - Dose …, 2018 - journals.sagepub.com
Thymoquinone (TQ), one of the main components active of Nigella sativa, exhibited very
useful biomedical effects such as anti-inflammatory, antioxidant, antimicrobial, antiparasitic …

Neurobiology of vitamin C: Expanding the focus from antioxidant to endogenous neuromodulator

SJ Ballaz, GV Rebec - Pharmacological research, 2019 - Elsevier
Ascorbic acid (AA) is a water-soluble vitamin (C) found in all bodily organs. Most mammals
synthesize it, humans are required to eat it, but all mammals need it for healthy functioning …

Synthesis and Optimization of Chitosan Nanoparticles Loaded with l-Ascorbic Acid and Thymoquinone

N Othman, MJ Masarudin, CY Kuen, NA Dasuan… - Nanomaterials, 2018 - mdpi.com
The combination of compounds with different classes (hydrophobic and hydrophilic
characters) in single chitosan carrier is a challenge due to the hydrophilicity of chitosan …

Carveol Attenuates Seizure Severity and Neuroinflammation in Pentylenetetrazole‐Kindled Epileptic Rats by Regulating the Nrf2 Signaling Pathway

AM Alvi, LT Al Kury, A Alattar, I Ullah… - Oxidative medicine …, 2021 - Wiley Online Library
Epilepsy is a neurodegenerative brain disorder characterized by recurrent seizure attacks.
Numerous studies have suggested a strong correlation between oxidative stress and …

Can essential oils provide an alternative adjuvant therapy for COVID-19 infections and pain management at the same time?

R Damiescu, DYW Lee, T Efferth - Pharmaceuticals, 2022 - mdpi.com
The active compounds from essential oils have been an important asset in treating different
diseases for many centuries. Nowadays, there are various available formulations used as …

The effects of various essential oils on epilepsy and acute seizure: a systematic review

TA Bahr, D Rodriguez, C Beaumont… - Evidence‐Based …, 2019 - Wiley Online Library
Many essential oils (EOs) have anticonvulsant activity and might benefit people with
epilepsy. Lemongrass, lavender, clove, dill, and other EOs containing constituents such as …

Therapeutic perspectives of the black cumin component thymoquinone: A review

C Sarkar, S Jamaddar, T Islam, M Mondal, MT Islam… - Food & Function, 2021 - pubs.rsc.org
The dietary phytochemical thymoquinone (TQ), belonging to the family of quinones, mainly
obtained from the black and angular seeds of Nigella sativa, is one of the promising …

Neuropharmacological potential and delivery prospects of thymoquinone for neurological disorders

M Jakaria, DY Cho, M Ezazul Haque… - Oxidative medicine …, 2018 - Wiley Online Library
Thymoquinone (TQ) is an active ingredient isolated from Nigella sativa and has various
pharmacological activities, such as protection against oxidative stress, inflammation, and …

Therapeutic implications of phosphorylation-and dephosphorylation-dependent factors of cAMP-response element-binding protein (CREB) in neurodegeneration

N Khakha, H Khan, A Kaur, TG Singh - Pharmacological Reports, 2023 - Springer
Neurodegeneration is a condition of the central nervous system (CNS) characterized by loss
of neural structures and function. The most common neurodegenerative disorders (NDDs) …

Natural terpenoids as a promising source for modulation of GABAergic system and treatment of neurological diseases

A Manayi, SM Nabavi, M Daglia, S Jafari - Pharmacological Reports, 2016 - Springer
Abstract γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter reducing neural
excitability in the mammalian central nervous system (CNS) with three subclasses of …