[HTML][HTML] Embryo model completes gastrulation to neurulation and organogenesis
G Amadei, CE Handford, C Qiu, J De Jonghe… - Nature, 2022 - nature.com
Embryonic stem (ES) cells can undergo many aspects of mammalian embryogenesis in
vitro,,,–, but their developmental potential is substantially extended by interactions with …
vitro,,,–, but their developmental potential is substantially extended by interactions with …
The placenta: epigenetic insights into trophoblast developmental models of a generation-bridging organ with long-lasting impact on lifelong health
M Hemberger, W Dean - Physiological Reviews, 2023 - journals.physiology.org
The placenta is a unique organ system that functionally combines both maternal and fetal
cell types with distinct lineage origins. Normal placentation is critical for developmental …
cell types with distinct lineage origins. Normal placentation is critical for developmental …
[HTML][HTML] In vitro embryogenesis and gastrulation using stem cells in mice and humans
SY Oh, SB Na, YK Kang, JT Do - International Journal of Molecular …, 2023 - mdpi.com
During early mammalian embryonic development, fertilized one-cell embryos develop into
pre-implantation blastocysts and subsequently establish three germ layers through …
pre-implantation blastocysts and subsequently establish three germ layers through …
Dissecting embryonic and extraembryonic lineage crosstalk with stem cell co-culture
Embryogenesis necessitates harmonious coordination between embryonic and
extraembryonic tissues. Although stem cells of both embryonic and extraembryonic origins …
extraembryonic tissues. Although stem cells of both embryonic and extraembryonic origins …
Journey of the mouse primitive endoderm: from specification to maturation
S Chowdhary… - … Transactions of the …, 2022 - royalsocietypublishing.org
The blastocyst is a conserved stage and distinct milestone in the development of the
mammalian embryo. Blastocyst stage embryos comprise three cell lineages which arise …
mammalian embryo. Blastocyst stage embryos comprise three cell lineages which arise …
[HTML][HTML] Tissue-intrinsic beta-catenin signals antagonize Nodal-driven anterior visceral endoderm differentiation
S Schumacher, M Fernkorn, M Marten, R Chen… - Nature …, 2024 - nature.com
The anterior-posterior axis of the mammalian embryo is laid down by the anterior visceral
endoderm (AVE), an extraembryonic signaling center that is specified within the visceral …
endoderm (AVE), an extraembryonic signaling center that is specified within the visceral …
Tissue-intrinsic Wnt signals antagonize Nodal-driven AVE differentiation
S Schumacher, M Fernkorn, M Marten, YS Kim… - BioRxiv, 2023 - biorxiv.org
The anterior-posterior axis of the mammalian embryo is laid down by the anterior visceral
endoderm (AVE), an extraembryonic signaling center that is specified within the visceral …
endoderm (AVE), an extraembryonic signaling center that is specified within the visceral …
In vitro Embryogenesis and Gastrulation using Stem Cells
SY Oh, SB Na, YK Kang, JT Do - 2023 - preprints.org
During early embryonic development, fertilized one-cell embryos develop into
preimplantation blastocysts and subsequently establish three germ layers through …
preimplantation blastocysts and subsequently establish three germ layers through …
Chemically induced cell plasticity enables the generation of high-fidelity embryo model
JCR Silva, H Li, J Huang, W Guan, J Wu, H Luo… - bioRxiv, 2024 - biorxiv.org
Embryo models open exciting opportunities for improving our understanding of development
and advancing medicine. However, current models depend on intricate procedures and the …
and advancing medicine. However, current models depend on intricate procedures and the …