Total HIV-1 DNA, a marker of viral reservoir dynamics with clinical implications
V Avettand-Fènoël, L Hocqueloux… - Clinical microbiology …, 2016 - Am Soc Microbiol
SUMMARY HIV-1 DNA persists in infected cells despite combined antiretroviral therapy
(cART), forming viral reservoirs. Recent trials of strategies targeting latent HIV reservoirs …
(cART), forming viral reservoirs. Recent trials of strategies targeting latent HIV reservoirs …
Measuring the success of HIV-1 cure strategies
J Thomas, A Ruggiero, WA Paxton… - Frontiers in cellular and …, 2020 - frontiersin.org
HIV-1 eradication strategies aim to achieve viral remission in the absence of antiretroviral
therapy (ART). The development of an HIV-1 cure remains challenging due to the latent …
therapy (ART). The development of an HIV-1 cure remains challenging due to the latent …
[图书][B] Advanced techniques in diagnostic microbiology
YW Tang, CW Stratton, YW Tang - 2013 - Springer
Medical microbiology is a branch of medical science that deals with the prevention,
diagnosis, and therapy of infectious diseases. A clinical microbiologist is a professional …
diagnosis, and therapy of infectious diseases. A clinical microbiologist is a professional …
CD4 cell count and HIV DNA level are independent predictors of disease progression after primary HIV type 1 infection in untreated patients
C Goujard, M Bonarek, L Meyer… - Clinical Infectious …, 2006 - academic.oup.com
Background. Treatment initiation at the time of primary human immunodeficiency virus (HIV)
type 1 (HIV-1) infection has become less frequent in recent years. Methods. In the French …
type 1 (HIV-1) infection has become less frequent in recent years. Methods. In the French …
A universal real-time PCR assay for the quantification of group-M HIV-1 proviral load
MS Malnati, G Scarlatti, F Gatto, F Salvatori… - Nature protocols, 2008 - nature.com
Quantification of human immunodeficiency virus type-1 (HIV-1) proviral DNA is increasingly
used to measure the HIV-1 cellular reservoirs, a helpful marker to evaluate the efficacy of …
used to measure the HIV-1 cellular reservoirs, a helpful marker to evaluate the efficacy of …
Macrophages archive HIV‐1 virions for dissemination in trans
N Sharova, C Swingler, M Sharkey… - The EMBO journal, 2005 - embopress.org
Viruses have evolved various strategies in order to persist within the host. To date, most
information on mechanisms of HIV‐1 persistence has been derived from studies with …
information on mechanisms of HIV‐1 persistence has been derived from studies with …
Impact of the timing of initiation of antiretroviral therapy during primary HIV-1 infection on the decay of cell-associated HIV-DNA
M Laanani, J Ghosn, A Essat, A Melard… - Clinical Infectious …, 2015 - academic.oup.com
Background. Combined antiretroviral therapy (cART) initiation during primary human
immunodeficiency virus (HIV) infection (PHI) yields a larger decrease in cell-associated HIV …
immunodeficiency virus (HIV) infection (PHI) yields a larger decrease in cell-associated HIV …
Distinct genetic loci control plasma HIV-RNA and cellular HIV-DNA levels in HIV-1 infection: the ANRS Genome Wide Association 01 study
C Dalmasso, W Carpentier, L Meyer, C Rouzioux… - PloS one, 2008 - journals.plos.org
Previous studies of the HIV-1 disease have shown that HLA and Chemokine receptor
genetic variants influence disease progression and early viral load. We performed a …
genetic variants influence disease progression and early viral load. We performed a …
Impact of 5 years of maximally successful highly active antiretroviral therapy on CD4 cell count and HIV-1 DNA level
JP Viard, M Burgard, JB Hubert, L Aaron, C Rabian… - Aids, 2004 - journals.lww.com
Objectives: To evaluate the impact on CD4 cell count and HIV-1 DNA level in peripheral
blood mononuclear cells (PBMC) of long-term highly active antiretroviral therapy (HAART) in …
blood mononuclear cells (PBMC) of long-term highly active antiretroviral therapy (HAART) in …
[HTML][HTML] Cell-associated HIV-1 RNA predicts viral rebound and disease progression after discontinuation of temporary early ART
AO Pasternak, ML Grijsen, FW Wit, M Bakker… - JCI insight, 2020 - ncbi.nlm.nih.gov
Plasma viral load (VL) and CD4+ T cell count are widely used as biomarkers of HIV type 1
(HIV-1) replication, pathogenesis, and response to antiretroviral therapy (ART). However …
(HIV-1) replication, pathogenesis, and response to antiretroviral therapy (ART). However …