Recent advances in bioprocessing application of membrane chromatography
Compared to traditional chromatography using resins in packed-bed columns, membrane
chromatography is a relatively new and immature bioseparation technology based on the …
chromatography is a relatively new and immature bioseparation technology based on the …
Polymer brushes for membrane separations: a review
The fundamentals and applications of polymer brush-modified membranes are reviewed.
This new class of synthetic membranes is explored with an emphasis on tuning the …
This new class of synthetic membranes is explored with an emphasis on tuning the …
Predictive scaling of fiber‐based protein A capture chromatography using mechanistic modeling
T Hahn, T Trunzer, F Rusly, R Zolyomi… - Biotechnology and …, 2024 - Wiley Online Library
Protein A affinity chromatography is an important step in the purification of monoclonal
antibodies (mAbs) and mAb‐derived biotherapeutics. While the biopharma industry has …
antibodies (mAbs) and mAb‐derived biotherapeutics. While the biopharma industry has …
Electrospun nanofibrous composite materials: a versatile platform for high efficiency protein adsorption and separation
Highly effective separation and purification of protein are extremely important for the
development of pharmaceutical industry, which still remains a great challenge. As a kind of …
development of pharmaceutical industry, which still remains a great challenge. As a kind of …
Convection rather than diffusion for fast efficient mRNA vaccine purification
R Banik, TG Neuman, Z Hao, M Al Sharabati… - Separation and …, 2025 - Elsevier
In the rush to produce mRNA vaccines and ensure integrity and purity, capital-intensive
purification steps were used, typically involving slow diffusion-driven, inefficient, and costly …
purification steps were used, typically involving slow diffusion-driven, inefficient, and costly …
A laterally-fed membrane chromatography module
P Madadkar, Q Wu, R Ghosh - Journal of Membrane Science, 2015 - Elsevier
Module design is of critical importance in membrane chromatography as the efficiency of
separation is highly dependent on fluid flow distribution and collection within the membrane …
separation is highly dependent on fluid flow distribution and collection within the membrane …
Chromatography bioseparation technologies and in-silico modelings for continuous production of biotherapeutics
K Behere, S Yoon - Journal of Chromatography A, 2020 - Elsevier
The potential of continuous bioprocessing is hindered by the bottlenecks of chromatography
processing, which continues to be executed in batch mode. Highlighting the critical …
processing, which continues to be executed in batch mode. Highlighting the critical …
Dynamic evaluation of polypropylene capillary‐channeled fibers as a stationary phase in high‐performance liquid chromatography
KM Randunu, S Dimartino… - Journal of separation …, 2012 - Wiley Online Library
Polypropylene (PP) capillary‐channeled polymer (C‐CP) fiber stationary phases are
investigated for applications in HPLC. Specifically, the roles that fiber size and shape, linear …
investigated for applications in HPLC. Specifically, the roles that fiber size and shape, linear …
Protein A affinity chromatography of Chinese hamster ovary (CHO) cell culture broths containing biopharmaceutical monoclonal antibody (mAb): Experiments and …
M Grom, M Kozorog, S Caserman, A Pohar… - … of Chromatography B, 2018 - Elsevier
Protein A-based affinity chromatography is a highly-efficient separation method to capture,
purify and isolate biosimilar monoclonal antibodies (mAb)–an important medical product of …
purify and isolate biosimilar monoclonal antibodies (mAb)–an important medical product of …
Polysulfone-graft-4′-aminobenzo-15-crown-5-ether based tandem membrane chromatography for efficient adsorptive separation of lithium isotopes
Adsorptive membrane-based chromatography can provide the high separation efficiency
common to column chromatography but at a lower working pressure. Herein, a novel …
common to column chromatography but at a lower working pressure. Herein, a novel …