Tumor biomarkers for diagnosis, prognosis and targeted therapy
Y Zhou, L Tao, J Qiu, J Xu, X Yang, Y Zhang… - … and Targeted Therapy, 2024 - nature.com
Tumor biomarkers, the substances which are produced by tumors or the body's responses to
tumors during tumorigenesis and progression, have been demonstrated to possess critical …
tumors during tumorigenesis and progression, have been demonstrated to possess critical …
Next-generation sequencing impact on cancer care: applications, challenges, and future directions
M Zalis, GG Viana Veloso, PN Aguiar Jr… - Frontiers in …, 2024 - frontiersin.org
Fundamentally precision oncology illustrates the path in which molecular profiling of tumors
can illuminate their biological behavior, diversity, and likely outcomes by identifying distinct …
can illuminate their biological behavior, diversity, and likely outcomes by identifying distinct …
Characterization of complex structural variation in the CYP2D6-CYP2D7-CYP2D8 gene loci using single-molecule long-read sequencing
AJ Turner, AD Derezinski, A Gaedigk… - Frontiers in …, 2023 - frontiersin.org
Complex regions in the human genome such as repeat motifs, pseudogenes and structural
(SVs) and copy number variations (CNVs) present ongoing challenges to accurate genetic …
(SVs) and copy number variations (CNVs) present ongoing challenges to accurate genetic …
The application of CRISPR-Cas in disease diagnosis and treatment
Z Wang, Y Liu, F Zhou, Y Wang, X Zhou - Science China Chemistry, 2023 - Springer
Clustered regularly interspaced short palindromic repeat (CRISPR) has been gaining much
attention in the modern medical field and has been widely used for the diagnosis and …
attention in the modern medical field and has been widely used for the diagnosis and …
Not Only Editing: A Cas-Cade of CRISPR/Cas-Based Tools for Functional Genomics in Plants and Animals
The advent of CRISPR/Cas9 technology has revolutionized genome editing, enabling the
attainment of once-unimaginable goals. CRISPR/Cas's groundbreaking attributes lie in its …
attainment of once-unimaginable goals. CRISPR/Cas's groundbreaking attributes lie in its …
A New Serotyping Method of Streptococcus pneumoniae Based on CRISPR/Cas9–Targeted Sequencing
Y Maladan, E Retnaningrum, BS Daryono… - The Journal of Molecular …, 2024 - Elsevier
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated
protein 9 (Cas9) application for targeted sequencing has made a breakthrough in the …
protein 9 (Cas9) application for targeted sequencing has made a breakthrough in the …
dmTGS: Precise Targeted Enrichment Long-Read Sequencing Panel for Tandem Repeat Detection
K Yang, Y Liu, J Zhang, Q Yu, F Xu, J Liu, Y Li… - Clinical …, 2024 - academic.oup.com
Abstract Background Tandem repeats (TRs) are abundant in the human genome and
associated with repeat expansion disorders. Our study aimed to develop a tandem repeat …
associated with repeat expansion disorders. Our study aimed to develop a tandem repeat …