The treat-to-target (T2T) concept has improved outcomes for patients with diabetes,
hypertension and rheumatoid arthritis. This therapeutic strategy involves choosing a well …

The current treatment approach for systemic lupus erythematosus (SLE), as outlined in the
recommendations by international medical associations including EULAR and the ACR, is …

Our objective was to update the EULAR recommendations for the management of systemic
lupus erythematosus (SLE), based on emerging new evidence. We performed a systematic …

Objective To achieve consensus on a definition of remission in SLE (DORIS). Background
Remission is the stated goal for both patient and caregiver, but consensus on a definition of …

Objectives To compare the efficacy to prevent flares of maintenance versus withdrawal of 5
mg/day prednisone in systemic lupus erythematosus (SLE) patients with clinically quiescent …

Objective In systemic lupus erythematosus (SLE) patients, excessive formation of neutrophil
extracellular traps (NETs) is observed and their degradation is impaired. In vitro, immune …

Objective One objective in the treatment of systemic lupus erythematosus (SLE) disease
activity is to reduce long‐term rates of organ damage. We undertook this study to analyze …

Objective To evaluate the prevalence, duration and effect on damage accrual of the 'Lupus
Low Disease Activity State'(LLDAS) in a monocentric cohort of patients with systemic lupus …

Background Treat-to-target strategies have improved outcomes in single-organ diseases
with simple clinical or laboratory endpoints. A lack of validated endpoints has prevented …

Background Systemic lupus erythematosus (SLE) management objectives include
preventing disease flares while minimizing glucocorticoid exposure. Pooled data from the …