Protein structural transitions critically transform the network connectivity and viscoelasticity of RNA-binding protein condensates but RNA can prevent it
AR Tejedor, I Sanchez-Burgos… - Nature …, 2022 - nature.com
Biomolecular condensates, some of which are liquid-like during health, can age over time
becoming gel-like pathological systems. One potential source of loss of liquid-like properties …
becoming gel-like pathological systems. One potential source of loss of liquid-like properties …
Rotaxane Formation of Multicyclic Polydimethylsiloxane in a Silicone Network: A Step toward Constructing “Macro‐Rotaxanes” from High‐Molecular‐Weight Axle and …
M Ebe, A Soga, K Fujiwara, BJ Ree… - Angewandte …, 2023 - Wiley Online Library
Rotaxanes consisting of a high‐molecular‐weight axle and wheel components (macro‐
rotaxanes) have high structural freedom, and are attractive for soft‐material applications …
rotaxanes) have high structural freedom, and are attractive for soft‐material applications …
Time-dependent material properties of aging biomolecular condensates from different viscoelasticity measurements in molecular dynamics simulations
AR Tejedor, R Collepardo-Guevara… - The Journal of …, 2023 - ACS Publications
Biomolecular condensates are important contributors to the internal organization of the cell
material. While initially described as liquid-like droplets, the term biomolecular condensates …
material. While initially described as liquid-like droplets, the term biomolecular condensates …
Nucleation and crystallization of polymer melts under cyclic stretching: entanglement effect
C Zhu, J Zhao - Macromolecules, 2023 - ACS Publications
It is well known that the local orientation order plays a key role in stretch-induced nucleation
and crystal growth of polymer melts, where a competition between chain orientation and …
and crystal growth of polymer melts, where a competition between chain orientation and …
[HTML][HTML] Composite entanglement topology and extensional rheology of symmetric ring-linear polymer blends
Extensive molecular simulations are applied to characterize the equilibrium dynamics,
entanglement topology, and nonlinear extensional rheology of symmetric ring-linear …
entanglement topology, and nonlinear extensional rheology of symmetric ring-linear …
Molecular dynamics simulations of ring shapes on a ring fraction in ring–linear polymer blends
K Hagita, T Murashima - Macromolecules, 2021 - ACS Publications
Threading of a linear chain through a ring has been known to have a strong effect on
slowing the dynamics of the ring. To enhance the toughness of soft materials using ring …
slowing the dynamics of the ring. To enhance the toughness of soft materials using ring …
All-Atom Molecular Dynamics Simulations of Poly (ethylene glycol) Networks in Water for Evaluating Negative Energetic Elasticity
We performed all-atom molecular dynamics simulations on poly (ethylene glycol)(PEG)
hydrogels to microscopically confirm the recently discovered “negative energetic …
hydrogels to microscopically confirm the recently discovered “negative energetic …
Measuring topological constraint relaxation in ring-linear polymer blends
Polymers are an effective test bed for studying topological constraints in condensed matter
due to a wide array of synthetically available chain topologies. When linear and ring …
due to a wide array of synthetically available chain topologies. When linear and ring …
Location and Concentration of Aromatic‐Rich Segments Dictates the Percolating Inter‐Molecular Network and Viscoelastic Properties of Ageing Condensates
Maturation of functional liquid‐like biomolecular condensates into solid‐like aggregates has
been linked to the onset of several neurodegenerative disorders. Low‐complexity aromatic …
been linked to the onset of several neurodegenerative disorders. Low‐complexity aromatic …
Effect of threading on static and dynamic properties of polymer chains in entangled linear-ring blend systems with different stiffness
W Wang, J Lu, R Sun - Polymer, 2024 - Elsevier
Threading is a unique topological state in linear/ring polymer blends (LRB), which is
considered to be essential for evaluating both the static and dynamic properties of ring …
considered to be essential for evaluating both the static and dynamic properties of ring …