The C Factor: Cognitive dysfunction as a transdiagnostic dimension in psychopathology

A Abramovitch, T Short, A Schweiger - Clinical Psychology Review, 2021 - Elsevier
Research into cognitive functions across psychological disorders suggests that cognitive
deficiencies may be present across multiple disorders, potentially pointing to a …

Appropriate use of bifactor analysis in psychopathology research: Appreciating benefits and limitations

MA Bornovalova, AM Choate, H Fatimah… - Biological …, 2020 - Elsevier
Co-occurrence of psychiatric disorders is well documented. Recent quantitative efforts have
moved toward an understanding of this phenomenon, with the general psychopathology or p …

Meta-analysis of structural evidence for the Hierarchical Taxonomy of Psychopathology (HiTOP) model

WR Ringwald, MK Forbes, AGC Wright - Psychological medicine, 2023 - cambridge.org
Background The Hierarchical Taxonomy of Psychopathology (HiTOP) is a classification
system that seeks to organize psychopathology using quantitative evidence–yet the current …

Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): III. Emotional dysfunction superspectrum

D Watson, HF Levin‐Aspenson, MA Waszczuk… - World …, 2022 - Wiley Online Library
The Hierarchical Taxonomy of Psychopathology (HiTOP) is a quantitative nosological
system that addresses shortcomings of traditional mental disorder diagnoses, including …

A critical evaluation of the p-factor literature

AL Watts, AL Greene, W Bonifay, EI Fried - Nature Reviews Psychology, 2024 - nature.com
The p-factor is a construct that is thought to explain and maybe even cause variation in all
forms of psychopathology. Since its 'discovery'in 2012, hundreds of studies have been …

The contribution of copy number variants to psychiatric symptoms and cognitive ability

J Mollon, L Almasy, S Jacquemont, DC Glahn - Molecular psychiatry, 2023 - nature.com
Copy number variants (CNVs) are deletions and duplications of DNA sequence. The most
frequently studied CNVs, which are described in this review, are recurrent CNVs that occur …

Dimensional and transdiagnostic phenotypes in psychiatric genome-wide association studies

MA Waszczuk, KG Jonas, M Bornovalova, G Breen… - Molecular …, 2023 - nature.com
Genome-wide association studies (GWAS) provide biological insights into disease onset
and progression and have potential to produce clinically useful biomarkers. A growing body …

The general factor of psychopathology (p): Choosing among competing models and interpreting p

A Caspi, RM Houts, HL Fisher… - Clinical …, 2024 - journals.sagepub.com
Over the past 10 years, the general factor of psychopathology, p, has attracted interest and
scrutiny. We review the history of the idea that all mental disorders share something in …

Research Review: A guide to computing and implementing polygenic scores in developmental research

AG Allegrini, JR Baldwin, W Barkhuizen… - Journal of Child …, 2022 - Wiley Online Library
The increasing availability of genotype data in longitudinal population‐and family‐based
samples provides opportunities for using polygenic scores (PGS) to study developmental …

Genetic architecture of ADHD and overlap with other psychiatric disorders and cognition-related phenotypes

M Ribasés, M Mitjans, CA Hartman, MS Artigas… - Neuroscience & …, 2023 - Elsevier
Attention-deficit/hyperactivity disorder (ADHD) co-occurs with many other psychiatric
disorders and traits. In this review, we summarize and interpret the existing literature on the …