Pyroptosis: mechanisms and diseases

P Yu, X Zhang, N Liu, L Tang, C Peng… - Signal transduction and …, 2021 - nature.com
Currently, pyroptosis has received more and more attention because of its association with
innate immunity and disease. The research scope of pyroptosis has expanded with the …

[HTML][HTML] Beyond the stomach: an updated view of Helicobacter pylori pathogenesis, diagnosis, and treatment

TL Testerman, J Morris - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) is an extremely common, yet underappreciated, pathogen that
is able to alter host physiology and subvert the host immune response, allowing it to persist …

LINC01133 as ceRNA inhibits gastric cancer progression by sponging miR-106a-3p to regulate APC expression and the Wnt/β-catenin pathway

XZ Yang, TT Cheng, QJ He, ZY Lei, J Chi, Z Tang… - Molecular cancer, 2018 - Springer
Background Gastric cancer (GC) is a common malignancy and frequent cause of cancer-
related death. Long non-coding RNAs (lncRNAs) have emerged as important regulators and …

[HTML][HTML] Role of the Wnt/β-catenin pathway in gastric cancer: An in-depth literature review

MA Chiurillo - World journal of experimental medicine, 2015 - ncbi.nlm.nih.gov
Gastric cancer remains one of the most common cancers worldwide and one of the leading
cause for cancer-related deaths. Gastric adenocarcinoma is a multifactorial disease that is …

[HTML][HTML] Carcinoma of the stomach: A review of epidemiology, pathogenesis, molecular genetics and chemoprevention

S Nagini - World journal of gastrointestinal oncology, 2012 - ncbi.nlm.nih.gov
Carcinoma of the stomach is still the second most common cause of cancer death
worldwide, although the incidence and mortality have fallen dramatically over the last 50 …

Isolation, identification, and characterization of cancer stem cells: A review

MR Abbaszadegan, V Bagheri… - Journal of cellular …, 2017 - Wiley Online Library
Cancer stem cells (CSCs) or tumor‐initiating cells (TICs) as a small subset of neoplastic
cells are able to produce a tumor (tumorigenesis), maintain the population of tumorigenic …

Downregulation of gasdermin D promotes gastric cancer proliferation by regulating cell cycle‐related proteins

WJ Wang, D Chen, MZ Jiang, B Xu… - Journal of digestive …, 2018 - Wiley Online Library
OBJECTIVE To explore the relationship between gasdermin D (GSDMD) and gastric cancer
(GC) cell proliferation, and to determine whether the downregulated expression of GSDMD …

The causes and consequences of polyploidy in normal development and cancer

T Davoli, T De Lange - Annual review of cell and developmental …, 2011 - annualreviews.org
Although nearly all mammalian species are diploid, whole-genome duplications occur in
select mammalian tissues as part of normal development. Such programmed …

The role of pyroptosis in gastrointestinal cancer and immune responses to intestinal microbial infection

CB Zhou, JY Fang - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2019 - Elsevier
Pyroptosis, a type of inflammatory programmed cell death, is mediated by multiple
inflammasomes which can recognize danger signals and activate the secretion of pro …

Wnt/β-catenin signaling as a molecular target by pathogenic bacteria

O Silva-García, JJ Valdez-Alarcón… - Frontiers in …, 2019 - frontiersin.org
The Wnt/β-catenin signaling pathway is crucial to regulate cell proliferation and polarity, cell
determination, and tissue homeostasis. The activation of Wnt/β-catenin signaling is based …