Adult mesenchymal stem cells (MSCs) and epithelial stem cells play essential roles in tissue
repair and self-healing. Oral MSCs and epithelial stem cells can be isolated from adult …

Background Ocular surface burns can be caused by chemicals (alkalis and acids) or by
direct heat. Amniotic membrane transplantation (AMT) performed in the acute phase (day 0 …

PURPOSE: To report the effectiveness, disease-specific outcomes, and safety of cultivated
oral mucosal epithelial sheet transplantation (COMET), with the primary objective of visual …

Ocular surface reconstruction with ex vivo expanded limbal stem cells (LSCs) is a widely
used clinical treatment for patients with limbal stem cell deficiency (LSCD). This is not …

The cornea is the outmost layer of the eye, unique in its transparency and strength. The
cornea not only transmits the light essential for vision, also refracts light, giving focus to …

Destruction or dysfunction of limbal epithelial stem cells (LESCs) leads to unilateral or
bilateral limbal stem cell deficiency (LSCD). Fifteen years have passed since the first …

Corneal stem cell niches are located within the limbus of the eye and are believed to play an
important role in corneal regeneration. These niches are often lost in corneal disease or …

The application of human amniotic membrane (AM) has a wide spectrum of indications in
the treatment of ocular surface disorders. Transplantation of AM has been incorporated …

Limbal epithelial stem cells (LESCs) are a population of stem cells responsible for
maintenance and repair of the corneal surface. Injury and disease can result in a deficiency …

Amniotic membrane use for management of corneal limbal stem... : Current Opinion in
Ophthalmology Amniotic membrane use for management of corneal limbal stem cell deficiency …