Spatial metabolomics is a new field that has risen rapidly in recent years, using mass
spectrometry imaging (MSI) technology, such as matrix-assisted laser desorption ionization …

Lipid dysregulations have been critically implicated in Alzheimer's disease (AD) pathology.
Chemical analysis of amyloid-β (Aβ) plaque pathology in transgenic AD mouse models has …

Given the complexity of nervous tissues, understanding neurochemical pathophysiology
puts high demands on bioanalytical techniques with respect to specificity and sensitivity …

Background: Although sporadic Alzheimer's disease (AD) is a neurodegenerative disorder
of unknown etiology, familial AD is associated with specific gene mutations. A commonality …

Alzheimer's disease (AD) is a progressive neurological condition characterized by impaired
cognitive function and behavioral alterations. While AD research historically centered …

Inflammation is a complex process that accompanies many pathologies. Actually,
dysregulation of the inflammatory process is behind many autoimmune diseases. Thus …

Alzheimer's disease (AD) affects one in eight individuals over 65 and poses an immense
societal challenge. AD pathology is characterized by the formation of beta‐amyloid plaques …

Mass spectrometry imaging (MSI) was developed to visualize spatial chemical information
within tissues, thereby facilitating spatial multi‐omic analysis. However, due to the limited …

Mass spectrometry imaging (MSI) is a powerful technique for label-free spatial mapping of
multiple classes of biomolecules in tissue sections. However, differences in desorption and …