[HTML][HTML] From multi-omics approaches to personalized medicine in myocardial infarction

C Zhan, T Tang, E Wu, Y Zhang, M He, R Wu… - Frontiers in …, 2023 - frontiersin.org
Myocardial infarction (MI) is a prevalent cardiovascular disease characterized by myocardial
necrosis resulting from coronary artery ischemia and hypoxia, which can lead to severe …

PCSK9 (proprotein convertase subtilisin/kexin type 9) triggers vascular smooth muscle cell senescence and apoptosis: implication of its direct role in degenerative …

Y Guo, Z Tang, B Yan, H Yin, S Tai, J Peng… - … and Vascular Biology, 2022 - Am Heart Assoc
Objective: PCSK9 (proprotein convertase subtilisin/kexin type 9) plays a critical role in
cholesterol metabolism via the PCSK9–LDLR (low-density lipoprotein receptor) axis in the …

Reelin depletion protects against atherosclerosis by decreasing vascular adhesion of leukocytes

L Calvier, X Xian, RG Lee, A Sacharidou… - … , and vascular biology, 2021 - Am Heart Assoc
Objective: Reelin and its receptor Apoer2 (apolipoprotein E receptor 2) play a prominent role
in endothelial cell dysfunction by promoting leukocyte–endothelial cell adhesion, an …

ApoER2 (Apolipoprotein E Receptor-2) deficiency accelerates smooth muscle cell senescence via cytokinesis impairment and promotes fibrotic neointima after …

RK Komaravolu, MD Waltmann… - … , and vascular biology, 2019 - Am Heart Assoc
Objective: Genome-wide studies showed that mutation in apoER2 (apolipoprotein E
receptor-2) is additive with ε4 polymorphism in the APOE gene on cardiovascular disease …

[HTML][HTML] miR-362-3p suppresses ovarian cancer by inhibiting LRP8

C Li, Y Yang, H Wang, Y Song, H Huang - Translational Oncology, 2022 - Elsevier
Background Ovarian cancer is one of the most common female cancers, with a high
incidence worldwide. Aberrant expression of low‐density lipoprotein (LDL) receptor‐related …

Mir-1322 protects against the myocardial ischemia Via Lrp8/Pi3k/Akt pathway

J Wei, J Cui - Biochemical and Biophysical Research …, 2023 - Elsevier
Introduction Myocardial infarction is a fatal disease that causes millions of deaths worldwide
every year. The damage and recovery of cardiomyocytes are closely related to changes in …

[HTML][HTML] Role of DNA Methylation in Development of Cardiovascular Diseases, Resulting in a Sudden Cardiac Death

АА Ivanova, SV Maksimova… - … технологии в медицине, 2022 - cyberleninka.ru
An effective system to diagnose predisposition to development of sudden cardiac death
(SCD) is required in order to determine the risk of developing a sudden fatal outcome well in …

[HTML][HTML] A haplotype of the phosphodiesterase 4D (PDE4D) gene is associated with myocardial infarction and with cardiometabolic parameters: the GEA study

JM Rodríguez-Pérez, R Posadas-Sánchez… - EXCLI …, 2018 - ncbi.nlm.nih.gov
The phosphodiesterase family is involved in a wide spectrum of diseases, including
ischemic stroke. However, few studies have analyzed the relationship between …

[HTML][HTML] РОЛЬ МЕТИЛИРОВАНИЯ ДНК В РАЗВИТИИ СЕРДЕЧНО-СОСУДИСТЫХ ЗАБОЛЕВАНИЙ, ПРИВОДЯЩИХ К ВНЕЗАПНОЙ СЕРДЕЧНОЙ СМЕРТИ …

АА Иванова, СВ Максимова… - … технологии в медицине, 2022 - cyberleninka.ru
Для определения риска развития внезапного летального исхода задолго до его
наступления, в том числе у лиц с бессимптомным течением сердечно-сосудистой …

[HTML][HTML] A substitution mutation in LRP8 gene is significantly associated with susceptibility to familial myocardial infarction

MJ Ghorbani, N Razmi, SMB Tabei… - ARYA …, 2020 - ncbi.nlm.nih.gov
BACKGROUND Myocardial infarction (MI) is a multifactorial disease caused by the
suspension of blood circulation in a part of the myocardium. Understanding the genetic …