[HTML][HTML] Smooth muscle ion channels and regulation of vascular tone in resistance arteries and arterioles
NR Tykocki, EM Boerman… - Comprehensive Physiology, 2017 - ncbi.nlm.nih.gov
Vascular tone of resistance arteries and arterioles determines peripheral vascular
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …
Calcium-activated potassium channels and the regulation of vascular tone
J Ledoux, ME Werner, JE Brayden, MT Nelson - Physiology, 2006 - journals.physiology.org
Different calcium signals in the endothelium and smooth muscle target different types of
Ca2+-sensitive K+ channels to modulate vascular function. These differential calcium …
Ca2+-sensitive K+ channels to modulate vascular function. These differential calcium …
Calcium‐activated potassium channels and endothelial dysfunction: therapeutic options?
M Félétou - British journal of pharmacology, 2009 - Wiley Online Library
The three subtypes of calcium‐activated potassium channels (KCa) of large, intermediate
and small conductance (BKCa, IKCa and SKCa) are present in the vascular wall. In healthy …
and small conductance (BKCa, IKCa and SKCa) are present in the vascular wall. In healthy …
Calcium-and voltage-gated BK channels in vascular smooth muscle
Ion channels in vascular smooth muscle regulate myogenic tone and vessel contractility. In
particular, activation of calcium-and voltage-gated potassium channels of large conductance …
particular, activation of calcium-and voltage-gated potassium channels of large conductance …
MaxiK channel partners: physiological impact
The basic functional unit of the large‐conductance, voltage‐and Ca2+‐activated K+ (MaxiK,
BK, BKCa) channel is a tetramer of the pore‐forming α‐subunit (MaxiKα) encoded by a …
BK, BKCa) channel is a tetramer of the pore‐forming α‐subunit (MaxiKα) encoded by a …
Vascular calcium signalling and ageing
Abstract Changes in cellular Ca2+ levels have major influences on vascular function and
blood pressure regulation. Vascular smooth muscle cells (SMCs) and endothelial cells …
blood pressure regulation. Vascular smooth muscle cells (SMCs) and endothelial cells …
[HTML][HTML] Large conductance, Ca2+-activated K+ channels (BKCa) and arteriolar myogenic signaling
Myogenic, or pressure-induced, vasoconstriction is critical for local blood flow
autoregulation. Underlying this vascular smooth muscle (VSM) response are events …
autoregulation. Underlying this vascular smooth muscle (VSM) response are events …
Role of hydrogen sulfide in cardiovascular ageing
L Testai, V Citi, A Martelli, S Brogi… - Pharmacological Research, 2020 - Elsevier
Cardiovascular diseases are the main cause of morbidity and mortality in the Western
society and ageing is a relevant non-modifiable risk factor. Morphological and functional …
society and ageing is a relevant non-modifiable risk factor. Morphological and functional …
Erectile dysfunction in mice lacking the large‐conductance calcium‐activated potassium (BK) channel
ME Werner, P Zvara, AL Meredith… - The Journal of …, 2005 - Wiley Online Library
Penile erection is dependent on the nitric oxide (NO)/cGMP‐dependent protein kinase I
(PKGI) pathway. One important target of PKGI in smooth muscle is the large‐conductance …
(PKGI) pathway. One important target of PKGI in smooth muscle is the large‐conductance …
Role of potassium channels in coronary vasodilation
K+ channels in coronary arterial smooth muscle cells (CASMC) determine the resting
membrane potential (E m) and serve as targets of endogenous and therapeutic vasodilators …
membrane potential (E m) and serve as targets of endogenous and therapeutic vasodilators …