The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

Classes of enteric nerve cells in the guinea‐pig small intestine

SJH Brookes - The Anatomical Record: An Official Publication …, 2001 - Wiley Online Library
The guinea‐pig small intestine has been very widely used to study the physiology,
pharmacology and morphology of the enteric nervous system. It also provides an ideal …

Beyond the microbiota: understanding the role of the enteric nervous system in Parkinson's disease from mice to human

M Montanari, P Imbriani, P Bonsi, G Martella, A Peppe - Biomedicines, 2023 - mdpi.com
The enteric nervous system (ENS) is a nerve network composed of neurons and glial cells
that regulates the motor and secretory functions of the gastrointestinal (GI) tract. There is …

The gut microbiome restores intrinsic and extrinsic nerve function in germ‐free mice accompanied by changes in calbindin

KA McVey Neufeld, A Perez‐Burgos… - …, 2015 - Wiley Online Library
Background The microbiome is essential for normal myenteric intrinsic primary afferent
neuron (IPAN) excitability. These neurons control gut motility and modulate gut–brain …

Enteric neuroplasticity evoked by inflammation

V Vasina, G Barbara, L Talamonti, V Stanghellini… - Autonomic …, 2006 - Elsevier
Neuroplastic changes in the enteric nervous system (ENS) may be observed in
physiological states, such as development and aging, or occur as a consequence of different …

Neurons and glia in the enteric nervous system and epithelial barrier function

N Vergnolle, C Cirillo - Physiology, 2018 - journals.physiology.org
The intestinal epithelial barrier is the largest exchange surface between the body and the
external environment. Its functions are regulated by luminal, and also internal, components …

Enteric nervous system: development and developmental disturbances—part 1

D Newgreen, HM Young - Pediatric and Developmental Pathology, 2002 - Springer
This review, which is presented in two parts, summarizes and synthesizes current views on
the genetic, molecular, and cell biological underpinnings of the early embryonic phases of …

Mast cell tryptase and proteinase‐activated receptor 2 induce hyperexcitability of guinea‐pig submucosal neurons

DE Reed, C Barajas‐Lopez, G Cottrell… - The Journal of …, 2003 - Wiley Online Library
Mast cells that are in close proximity to autonomic and enteric nerves release several
mediators that cause neuronal hyperexcitability. This study examined whether mast cell …

Role of glutamatergic neurotransmission in the enteric nervous system and brain-gut axis in health and disease

V Filpa, E Moro, M Protasoni, F Crema, G Frigo… - …, 2016 - Elsevier
Several studies have been carried out in the last 30 years in the attempt to clarify the
possible role of glutamate as a neurotransmitter/neuromodulator in the gastrointestinal tract …

Correlation of electrophysiological and morphological characteristics of enteric neurons in the mouse colon

K Nurgali, MJ Stebbing… - Journal of Comparative …, 2004 - Wiley Online Library
We report on the first correlative study of the electrophysiological properties, shapes, and
projections of enteric neurons in the mouse. Neurons in the myenteric plexus of the mouse …