Saudi Arabian plants: A powerful weapon against a plethora of diseases

HR El-Seedi, SM Kotb, SG Musharraf, AA Shehata… - Plants, 2022 - mdpi.com
The kingdom of Saudi Arabia (SA) ranks fifth in Asia in terms of area. It features broad
biodiversity, including interesting flora, and was the historical origin of Islam. It is endowed …

Revisiting nature: a review of iridoids as a potential antileishmanial class

G Arraché Gonçalves, VL Eifler-Lima… - Phytochemistry …, 2022 - Springer
Leishmaniasis still stands as one of the most prevalent neglected tropical diseases in the
least developed and emerging countries. The recommended therapeutic arsenal to treat …

Novel phenolic compounds as potential dual EGFR and COX-2 inhibitors: Design, semisynthesis, in vitro biological evaluation and in silico Insights

MA Abdelgawad, A Musa, AH Almalki… - Drug design …, 2021 - Taylor & Francis
Introduction Epidermal growth factor receptor (EGFR) inhibition is an imperative therapeutic
approach targeting various types of cancer including colorectal, lung, breast, and pancreatic …

Iridoids from Morinda lucida,(Benth.) Rubiaceae, produced analgesic and anti-inflammatory activities via agonism at the kappa and delta opioid receptors, inhibition of …

EK Kumatia, F Ayertey, T Ohta, T Uto… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Pain and inflammation are the major symptoms of almost
every human disease. Herbal preparations from Morinda lucida are used to treat pain and …

Green Approach:''A Forwarding Step for Curing Leishmaniasis—A Neglected Tropical Disease''

L Sharma, M Dhiman, A Singh… - Frontiers in Molecular …, 2021 - frontiersin.org
The present review focuses on a dreaded vector-mediated leishmaniasis, with the existing
therapeutic approaches including a variety of drugs along with their limitations, the treatment …

[PDF][PDF] In silico study, protein kinase inhibition and antiproliferative potential of flavonoids isolated from Bassia eriophora (Schrad.) growing in KSA

A Musa, MM Al-Sanea, NH Alotaibi, TS Alnusaire… - Indian J. Pharm. Educ …, 2021 - ijper.org
Introduction: Kinase enzymes play an important role in cellular proliferation, the main target
in cancer treatment is to inhibit their functions. Protein kinase inhibitors as flavonoids can be …

[HTML][HTML] Phytochemistry, structural diversity, biological activities and pharmacokinetics of iridoids isolated from various genera of the family Scrophulariaceae Juss.

AA Thabet, IM Ayoub, FS Youssef, E Al-Sayed… - Phytomedicine Plus, 2022 - Elsevier
Background Iridoids are naturally occurring oxygenated monoterpenes with wide range of
pharmacological activities. Scrophulariaceae Juss. is a family of flowering plants with 74 …

Prominent antidiabetic and anticancer investigation of Scrophularia deserti extract: Integration of experimental and computational approaches

A Musa, SR Ahmed, S Hussein, KA Youssif… - Journal of Molecular …, 2024 - Elsevier
Diabetes mellitus (DM) is a group of syndromes and complications characterized by
hyperglycemia, metabolic disorders in lipids, carbohydrates, and proteins. It causes an …

[PDF][PDF] Repurposing of FDA approved alkaloids as COVID 19 inhibitors; in silico studies

EM Mostafa, M Gamal, MM Ghoneim… - Pharmacognosy …, 2021 - researchgate.net
Background: Alkaloid drugs were permitted for using as a treatment of numerous diseases.
Colchicine, codeine, piperine, papaverine, ergometrine, theophylline, theobromine and …

Anticancer activity of micromeria fruticosa and Teucrium polium growing in Lebanon

M Al-Hamwi, M Aboul-Ela, A El-Lakany… - Pharmacognosy …, 2021 - phcogj.com
The anticancer activities of two Lebanese plant extract Micromeria fruticose (A) and
Teucrium polium (B) and their fractions were tested against MCF7 and A549 cancer cell …