The community of microorganisms within the human gut (or microbiota) is critical to health
and functions with a level of complexity comparable to that of an organ system. Alterations of …

Irritable bowel syndrome (IBS) is a functional condition of the bowel that is diagnosed using
clinical criteria. This paper discusses the nature of the diagnostic process for IBS and how …

Irritable bowel syndrome (IBS) is the most prevalent of the functional gastrointestinal
disorders (FGIDs). Current estimates are that IBS affects up to 10–12% of adults in North …

Background & Aims Irritable bowel syndrome (IBS) is a common disorder of gut–brain
interaction associated with significant disease burden. This American Gastroenterological …

Background Irritable bowel syndrome (IBS) is a chronic functional disorder of the
gastrointestinal system affecting a large number of people worldwide. Whilst it has no …

Background & Aims Irritable bowel syndrome (IBS) is a common functional gastrointestinal
disorder associated with significant disease burden. This American Gastroenterological …

OBJECTIVES: Linaclotide is a minimally absorbed peptide guanylate cyclase-C agonist. The
objective of this trial was to determine the efficacy and safety of linaclotide treatment in …

Background and aim Current treatment for irritable bowel syndrome (IBS) is suboptimal.
Fermentable oligo‐, di‐, mono‐saccharides and polyols (FODMAPs) may trigger …

Background The intestinal microbiota has been implicated in the pathophysiology of irritable
bowel syndrome (IBS). Due to the variable resolutions of techniques used to characterize …

The human body contains as many bacteria in the intestine as the total number of human
body cells. These bacteria have a central position in human health and disease, and would …