BACKGROUND Infertility is a major issue in human reproductive health, affecting an
estimated 15% of couples worldwide. Infertility can result from disorders of sex development …

A complete gonadal dysgenesis (CGD) with 46, XY karyotype is known as the Swyer
syndrome and belongs to the group of 46, XY differences of sex development (DSD). The …

Summary Male‐to‐female 64, XY sex reversal is a frequently reported chromosome
abnormality in horses. Despite this, the molecular causes of the condition are as yet poorly …

Disorders of sex development (DSDs) are congenital conditions in which chromosomal,
gonadal and sex is atypical. It is difficult to diagnose and manage patients with DSD in …

In mammals, male sexual development is initiated by the expression of the Sex-determining-
Region-Y (SRY) gene. SRY contains a highly conserved High Mobility Group (HMG) box …

We aimed to survey the monogenic causes of disorders of sex development (DSD) and
thereby its prevalence in India. This study revealed mutations resulting in androgen …

Sex-determining region of the Y chromosome (SRY) gene plays a crucial role in male sexual
differentiation and development. Several mutations in the SRY gene have been reported in …

The male sex-determining gene, sex-determining region on the Y chromosome (SRY), is
expressed in adult testicular germ cells; however, its role in regulating spermatogenesis …

SRY is the Y‐chromosomal gene that determines male sex development in humans and
most other mammals. After three decades of study, we still lack a detailed understanding of …

Male sex determination in humans is controlled by the SRY gene, which encodes a
transcriptional regulator containing a conserved high mobility group box domain (HMG-box) …