The intrinsic and acquired resistance of Mycobacterium abscessus to commonly used
antibiotics limits the chemotherapeutic options for infections caused by these mycobacteria …

All organisms must sense and respond to their external environments, and this signal
transduction often involves second messengers such as cyclic nucleotides. One such …

INTRODUCTION Nearly all mycobacterial species are free-living environmental
saprophytes. A few, such as Mycobacterium tuberculosis, have evolved to cause …

The genus Mycobacterium is best known for its two major pathogenic species, M.
tuberculosis and M. leprae, the causative agents of two of the world's oldest diseases …

The pe/ppe genes represent one of the most intriguing aspects of the M ycobacterium
tuberculosis genome. These genes are especially abundant in pathogenic mycobacteria …

The human tuberculous granuloma provides the morphological framework for local immune
processes central to the outcome of tuberculosis. This review article describes investigations …

The genus Mycobacterium comprises a group of obligately aerobic bacteria that have
adapted to inhabit a wide range of intracellular and extracellular environments. A …

RNA sequencing provides a new perspective on the genome of Mycobacterium tuberculosis
by revealing an extensive presence of non-coding RNA, including long 5'and 3'untranslated …

Mycobacterium tuberculosis contains five resuscitation‐promoting factor (Rpf)‐like proteins,
RpfA‐E, that are implicated in resuscitation of this organism from dormancy via a mechanism …

We have recently demonstrated that the macrophage L-arginine-dependent cytotoxic
pathway effectively kills the virulent Erdman strain of Mycobacterium tuberculosis in vitro via …