Hypertrophic scars and keloids are fibroproliferative disorders that may arise after any deep
cutaneous injury caused by trauma, burns, surgery, etc. Hypertrophic scars and keloids are …

Bone is a hard yet dynamic tissue with remarkable healing capacities. Research to date has
greatly advanced the understanding of how bone heals and has led to marked success in …

Bone remodeling is a tightly regulated process securing repair of microdamage (targeted
remodeling) and replacement of old bone with new bone through sequential osteoclastic …

Mesenchymal stem cell (MSC) transplantation has proved to be a promising strategy in cell
therapy and regenerative medicine. Although their mechanism of action is not completely …

Tissue engineering has recently become available as a treatment procedure for bone
augmentation. However, this procedure has several problems, such as high capital …

Regeneration of bone and cartilage defects can be accelerated by localized delivery of
appropriate growth factors incorporated within biodegradable carriers. The carrier …

The lack of a functional vascular supply has, to a large extent, hampered the whole range of
clinical applications of 'successful'laboratory‐based bone tissue engineering strategies. To …

Stromal stem cells from human dental pulp (SBP-DPSCs) were used to study osteogenic
differentiation in vitro and in vivo. We previously reported that SBP-DPSCs are multipotent …

There is enormous worldwide demand for therapies to promote the efficient resolution of
hard-to-heal wounds with minimal appearance of scarring. Recent in vitro studies with …

Scars are a consequence of cutaneous wound healing that can be both unsightly and
detrimental to the function of the tissue. Scar tissue is generated by excessive deposition of …