Mitochondria as a cellular hub in infection and inflammation
Mitochondria are the energy center of the cell. They are found in the cell cytoplasm as
dynamic networks where they adapt energy production based on the cell's needs. They are …
dynamic networks where they adapt energy production based on the cell's needs. They are …
Antiviral potential of garlic (Allium sativum) and its organosulfur compounds: A systematic update of pre-clinical and clinical data
Abstract Background Garlic (Allium sativum L.) is a common herb consumed worldwide as
functional food and traditional remedy for the prevention of infectious diseases since ancient …
functional food and traditional remedy for the prevention of infectious diseases since ancient …
Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway
C Holze, C Michaudel, C Mackowiak, DA Haas… - Nature …, 2018 - nature.com
Reactive oxygen species (ROS) are generated by virus-infected cells; however, the
physiological importance of ROS generated under these conditions is unclear. Here we …
physiological importance of ROS generated under these conditions is unclear. Here we …
Pathogen recognition by the innate immune system
Microbial infection initiates complex interactions between the pathogen and the host.
Pathogens express several signature molecules, known as pathogen-associated molecular …
Pathogens express several signature molecules, known as pathogen-associated molecular …
Roles of oxidative stress and Nrf2 signaling in pathogenic and non-pathogenic cells: a possible general mechanism of resistance to therapy
M Hammad, M Raftari, R Cesário, R Salma, P Godoy… - Antioxidants, 2023 - mdpi.com
The coordinating role of nuclear factor erythroid-2-related factor 2 (Nrf2) in cellular function
is undeniable. Evidence indicates that this transcription factor exerts massive regulatory …
is undeniable. Evidence indicates that this transcription factor exerts massive regulatory …
Stress proteins: the biological functions in virus infection, present and challenges for target-based antiviral drug development
Q Wan, D Song, H Li, M He - Signal transduction and targeted therapy, 2020 - nature.com
Stress proteins (SPs) including heat-shock proteins (HSPs), RNA chaperones, and ER
associated stress proteins are molecular chaperones essential for cellular homeostasis. The …
associated stress proteins are molecular chaperones essential for cellular homeostasis. The …
Dengue virus infection: a tale of viral exploitations and host responses
N Nanaware, A Banerjee, S Mullick Bagchi, P Bagchi… - Viruses, 2021 - mdpi.com
Dengue is a mosquito-borne viral disease (arboviral) caused by the Dengue virus. It is one
of the prominent public health problems in tropical and subtropical regions with no effective …
of the prominent public health problems in tropical and subtropical regions with no effective …
[HTML][HTML] Regulation of innate immunity by Nrf2
D van der Horst, ME Carter-Timofte… - Current Opinion in …, 2022 - Elsevier
The transcription factor Nuclear factor erythroid 2-related factor 2 (Nrf2) has been mainly
investigated as a regulator of redox homeostasis. However, research over the past years …
investigated as a regulator of redox homeostasis. However, research over the past years …
Quantum sensing of free radicals in primary human dendritic cells
Free radicals are crucial indicators for stress and appear in all kinds of pathogenic
conditions, including cancer, cardiovascular diseases, and infection. However, they are …
conditions, including cancer, cardiovascular diseases, and infection. However, they are …
Pathobiology of Japanese encephalitis virus infection
Japanese encephalitis virus (JEV) is a flavivirus, spread by the bite of carrier Culex
mosquitoes. The subsequent disease caused is Japanese encephalitis (JE), which is the …
mosquitoes. The subsequent disease caused is Japanese encephalitis (JE), which is the …