Classic cadherins, which are known to be crucial for homotypic cell—cell adhesion, have
been found to be present not only in vertebrate but also in invertebrate species. Their three …

▪ Abstract The polarized architecture of epithelial cells and tissues is a fundamental
determinant of animal anatomy and physiology. Recent progress made in the genetic and …

Receptors for Wingless and other signalling molecules of the Wnt gene family have yet to be
identified. We show here that cultured Drosophila cells transfected with a novel member of …

The cytoplasmic domain of classical cadherins is tightly associated with three proteins
termed α-, β-and γ-catenin. These accessory proteins are of central importance for the …

Cadherins are involved in a variety of morphogenetic movements during animal
development. However, it has been difficult to pinpoint the precise function of cadherins in …

Cellularization of the Drosophila embryo results in the formation of a cell monolayer with
many characteristics of a polarized epithelium. We have used antibodies specific to cellular …

Adhesion molecules of the cadherin superfamily have an important role during vertebrate
development. The DE-cadherin homolog DE-cadherin is the first classic cadherin isolated …

ABSTRACT wingless/wnt-1 signaling directs cell fate during development. Genetic analysis
in Drosophila identified genes that may encode components of the wingless signal …

In Drosophila wing imaginal discs, the Wingless (Wg) protein acts as a morphogen,
emanating from the dorsal/ventral (D/V) boundary of the disc to directly define cell identities …

In a Drosophila follicle the oocyte always occupies a posterior position among a group of
sixteen germline cells. Although the importance of this cell arrangement for the subsequent …