In metabolic conditions such as obesity and diabetes, which are associated with
deregulated signaling of the insulin/insulin-like growth factor system (IIGFs), inflammation …

The progress of genetic engineering in the 1970s brought about a paradigm shift in genome
editing technology. The clustered regularly interspaced short palindromic repeats/CRISPR …

Protein kinase CK2 (CK2) is a ubiquitous holoenzyme involved in a wide array of
developmental processes. The involvement of CK2 in events such as neurogenesis …

Cancer is a complex and dynamic disease. The “hallmarks of cancer” were proposed by
Hanahan and Weinberg (2000) as a group of biological competencies that human cells …

Myometrial contraction is stringently controlled throughout pregnancy and parturition.
Progesterone signaling, effecting through the progesterone receptor (PR), is pivotal in …

The immune response mediated by Th17 cells is essential in the pathogenesis of
periodontitis. Emerging evidence has demonstrated that lipopolysaccharide from …

Childhood B-cell acute lymphoblastic leukemia (B-ALL) is a heterogeneous disease
comprising multiple molecular subgroups with subtype-specific expression profiles …

JAK/STAT (Janus Kinaz Dönüştürücüleri ve Transkripsiyon Aktivatörleri) sinyal yolağı, hücre
büyümesi, gelişmesi, hayatta kalma, tümör oluşumu ve hücre farklılaşması gibi birçok …

The involvement of the Janus Kinase (JAK) and Signal Transducer and Activator of
Transcription (STAT) signaling pathway in various human autoimmune diseases and …

Diffuse large B-cell lymphoma (DLBCL) is a highly heterogeneous and aggressive disease
and is the most common subtype of non-Hodgkin lymphoma (NHL) in adults. Additionally …