The septins are a novel family of proteins that were first recognized in yeast as proteins
associated with the neck filaments. Recent work has shown that septins are also present in …

BAR and ENTH domains are families of α-helical lipid bilayer binding modules found in
proteins that function in endocytosis, actin regulation and signaling. Several members of …

Pyrin, the familial Mediterranean fever protein, is found in association with the cytoskeleton
in myeloid/monocytic cells and modulates IL-1β processing, NF-κB activation, and …

We used fluorescence microscopy to measure global and local concentrations of 28
cytoskeletal and signaling proteins fused to yellow fluorescent protein (YFP) in the fission …

PAPA syndrome (pyogenic sterile arthritis, pyoderma gangrenosum, and acne, OMIM#
604416) and familial recurrent arthritis (FRA) are rare inherited disorders of early onset …

Cell-cycle control of transcription seems to be universal, but little is known about its global
conservation and biological significance. We report on the genome-wide transcriptional …

Microscopy of fluorescent fusion proteins and genetic dependencies show that fission yeast
assemble and constrict a cytokinetic contractile ring in a precisely timed, sequential order …

As in many other eukaryotic cells, cell division in fission yeast depends on the assembly of
an actin ring that circumscribes the middle of the cell. Schizosaccharomyces pombe cdc12 is …

The conserved FER-CIP4 homology (FCH) domain is found in the pombe Cdc15 homology
(PCH) protein family members, including formin-binding protein 17 (FBP17). However, the …

We observed live fission yeast expressing pairs of functional fluorescent fusion proteins to
test the popular model that the cytokinetic contractile ring assembles from a single myosin II …