Oral drug administration has been a popular choice due to patient compliance and limited
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …

Oral administration of pharmaceuticals is the most preferred route of administration for
patients, but it is challenging to effectively deliver active ingredients (APIs) that i) have …

Abstract Background Micro-and nanoplastics (MNPs) represent one of the most widespread
environmental pollutants of the twenty-first century to which all humans are orally exposed …

This study investigates the impact of charge and chain length of bile salts in the bilosomes
on the oral bioavailability of insulin (IN) by examining their uptake via the apical sodium …

Bile acid-modified nanomedicine is a promising strategy to improve oral bioavailability.
However, the efficiencies of different bile acids have not been clarified. To clarify this issue …

Background Despite the effectiveness of glucagon-like peptide-1 agonist (GLP-1A) in the
treatment of diabetes, its large molecular weight and high hydrophilicity result in poor …

Oral insulin therapies targeting the liver and further simulating close‐looped secretion face
significant challenges due to multiple trans‐epithelial barriers. Herein, ursodeoxycholic acid …

Despite the promising prospects of nanoparticles in oral drug delivery, the process of oral
administration involves a complex transportation pathway that includes cellular uptake …

Catechol-based biomaterials demonstrate biocompatibility, making them suitable for a wide
range of therapeutic applications when integrated into various molecular frameworks …

Statins are widely used to treat hyperlipidemia; however, their mechanism—inhibiting
cholesterol production without promoting its utilization—causes problems, such as inducing …