The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …

Depression and obesity are common conditions with major public health implications that
tend to co-occur within individuals. The relationship between these conditions is …

Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic …

Obesity is among the most threatening health burdens worldwide and its prevalence has
markedly increased over the last decades. Obesity maybe considered a heritable trait …

Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …

Polymorphisms in the fat mass and obesity-associated gene (FTO) are associated with
human obesity and obesity-prone behaviors, including increased food intake and a …

Background Single nucleotide polymorphism (SNP) arrays for domestic cattle have
catalyzed the identification of genetic markers associated with complex traits for inclusion in …

Innovations in epitranscriptomics have resulted in the identification of more than 160 RNA
modifications to date. These developments, together with the recent discovery of writers …

Although thousands of loci have been associated with human phenotypes, the role of gene-
environment (GxE) interactions in determining individual risk of human diseases remains …

abstract Background: Studies have suggested that the fat mass and obesity–associated
(FTO) genotype is associated with individual variability in weight loss in response to …