The number of biotechnology-based pharmaceuticals in the late-stage pipeline has been
increasing more than ever. As a result, there is an enhanced demand for more efficient and …

The therapeutic use of proteins has created an increasing demand for feasible and
economical methods for both up-and downstream processes. However, whereas upstream …

Advances in fermentation technologies have resulted in the production of increased yields of
proteins of economic, biopharmaceutical, and medicinal importance. Consequently, there is …

For half a century aqueous two‐phase systems (ATPSs) have been applied for the extraction
and purification of biomolecules. In spite of their simplicity, selectivity, and relatively low cost …

Quality by Design (QbD) is gaining industry acceptance as an approach towards
development and commercialization of biotechnology therapeutic products that are …

The development of recovery processes using aqueous two‐phase systems (ATPS) has
been limited by the extensive experimental work required to establish the optimal system …

Bioprocess development today is slow and expensive compared to chemical process
development. A drastic paradigm shift is necessary and possible by the consistent …

Aqueous two‐phase systems (ATPS) have proved to be an efficient and integrative
operation to enhance recovery of industrially relevant bioproducts. After ATPS discovery, a …

Background In industry and academic research, there is an increasing demand for flexible
automated microfermentation platforms with advanced sensing technology. However, up to …

Separation of 2, 3-butanediol from the fermentation broth is a difficult task that has become a
bottleneck in industrial production. Aqueous two-phase systems composed of hydrophilic …