[HTML][HTML] In-silico protein-ligand docking studies against the estrogen protein of breast cancer using pharmacophore based virtual screening approaches

JJ Sahayarayan, KS Rajan, R Vidhyavathi… - Saudi Journal of …, 2021 - Elsevier
Breast cancer in woman is the most common cancer and in 2018 there were around 2
million new cases recorded. The maximum rate of breast cancer is reported in Belgium …

Nanoscale modification of chrysin for improved of therapeutic efficiency and cytotoxicity

GM Sulaiman, MS Jabir, AH Hameed - Artificial cells, nanomedicine …, 2018 - Taylor & Francis
Chrysin, as a flavone, is a promising drug candidate because of its multifaceted properties,
such as anti-inflammatory, antioxidant and anticancer. However, its poor bioavailability is a …

Methods and strategies used in green chemistry: a review

A Sharma, S Wakode, S Sharma… - Current Organic …, 2020 - ingentaconnect.com
Green chemistry plays an important role in the development of sustainable production
systems which involves tremendous research efforts on the design of synthetic and …

Synthesized chrysin-loaded nanoliposomes improves cadmium-induced toxicity in mice

M Beyrami, E Karimi, E Oskoueian - Environmental Science and Pollution …, 2020 - Springer
In this study, chrysin as a natural flavonoid was encapsulated in nanoliposomal structures,
and the synthesized nanoliposome-loaded chrysin (NLC) was further characterized for its …

Structure Based docking studies towards exploring potential anti-androgen activity of selected phytochemicals against Prostate Cancer

AN Singh, MM Baruah, N Sharma - Scientific reports, 2017 - nature.com
Prostate cancer (PCa) is the second most common malignancy amongst men worldwide.
Under PCa maintenance therapy drugs acting as antagonists/partial agonists of hormone …

Exploration of selected monoterpenes as potential TRPC channel family modulator in lung cancer, an in-silico upshot

A Singh, A Mishra, A Meena, N Mishra… - Journal of Biomolecular …, 2024 - Taylor & Francis
Lung cancer is still the most frequent cause of cancer-related death, accounting for nearly
two million cases yearly. As cancer is a multifactorial disease, developing novel molecular …

Sequence to structure approach of estrogen receptor alpha and ligand interactions

A Chamkasem, W Toniti - Asian Pacific Journal of Cancer …, 2015 - koreascience.kr
Estrogen receptors (ERs) are steroid receptors located in the cytoplasm and on the nuclear
membrane. The sequence similarities of human $ ER {\alpha} $, mouse $ ER {\alpha} $, rat …

Exploration and evaluation of bioactive phytocompounds against BRCA proteins by in silico approach

H Prabhavathi, KR Dasegowda… - Journal of …, 2021 - Taylor & Francis
The proteins encoded by the two major breast cancer genes (BRCA1 and BRCA2), ensure
the stability of DNA and prevent uncontrolled cell growth; mutation of these genes is linked …

Anticancer drug discovery from Iranian Chrysanthemum cultivars through system pharmacology exploration and experimental validation

M Hodaei, M Rahimmalek, M Behbahani - Scientific Reports, 2021 - nature.com
Breast cancer is the most common carcinoma in women, and natural products would be
effective preventing some side effects of cancer treatment. In the present study, cytotoxic …

Effectiveness and Anticancer Activity of a Novel Phenolic Compound from Garcinia porrecta Against the MCF-7 Breast Cancer Cell Line in vitro and in silico

D Darwati, AN Safitri, N Ambardhani… - Drug Design …, 2021 - Taylor & Francis
Background Cancer is a leading cause of death worldwide, with breast cancer being the
most common invasive cancer type in women. Several therapeutic strategies have been …