Biology and systematics of Echinococcus

RCA Thompson - Advances in parasitology, 2017 - Elsevier
The biology of Echinococcus, the causative agent of echinococcosis (hydatid disease) is
reviewed with emphasis on the developmental biology of the adult and metacestode stages …

Exosomes and other extracellular vesicles: the new communicators in parasite infections

G Coakley, RM Maizels, AH Buck - Trends in parasitology, 2015 - cell.com
Extracellular vesicles (EVs) have emerged as a ubiquitous mechanism for transferring
information between cells and organisms across all three kingdoms of life. In addition to their …

The genomes of four tapeworm species reveal adaptations to parasitism

IJ Tsai, M Zarowiecki, N Holroyd, A Garciarrubio… - Nature, 2013 - nature.com
Tapeworms (Cestoda) cause neglected diseases that can be fatal and are difficult to treat,
owing to inefficient drugs. Here we present an analysis of tapeworm genome sequences …

[HTML][HTML] Host parasite communications—Messages from helminths for the immune system: Parasite communication and cell-cell interactions

G Coakley, AH Buck, RM Maizels - Molecular and Biochemical Parasitology, 2016 - Elsevier
Helminths are metazoan organisms many of which have evolved parasitic life styles
dependent on sophisticated manipulation of the host environment. Most notably, they down …

Extracellular vesicles from Echinococcus granulosus larval stage: Isolation, characterization and uptake by dendritic cells

MC Nicolao, C Rodriguez Rodrigues… - PLoS neglected …, 2019 - journals.plos.org
The secretion of extracellular vesicles (EVs) in helminth parasites is a constitutive
mechanism that promotes survival by improving their colonization and adaptation in the host …

Infection by the helminth parasite Fasciola hepatica requires rapid regulation of metabolic, virulence, and invasive factors to adjust to its mammalian host

K Cwiklinski, H Jewhurst, P McVeigh, T Barbour… - Molecular & Cellular …, 2018 - ASBMB
The parasite Fasciola hepatica infects a broad range of mammals with impunity. Following
ingestion of parasites (metacercariae) by the host, newly excysted juveniles (NEJ) emerge …

The unique stem cell system of the immortal larva of the human parasite Echinococcus multilocularis

U Koziol, T Rauschendorfer, L Zanon Rodríguez… - Evodevo, 2014 - Springer
Background It is believed that in tapeworms a separate population of undifferentiated cells,
the germinative cells, is the only source of cell proliferation throughout the life cycle (similar …

Echinococcus–host interactions at cellular and molecular levels

K Brehm, U Koziol - Advances in parasitology, 2017 - Elsevier
The potentially lethal zoonotic diseases alveolar and cystic echinococcosis are caused by
the metacestode larval stages of the tapeworms Echinococcus multilocularis and …

Echinococcus as a model system: biology and epidemiology

RCA Thompson, DJ Jenkins - International journal for parasitology, 2014 - Elsevier
The introduction of Echinococcus to Australia over 200 years ago and its establishment in
sheep rearing areas of the country inflicted a serious medical and economic burden on the …

Proteomic characterization of larval and adult developmental stages in Echinococcus granulosus reveals novel insight into host–parasite interactions

SJ Cui, LL Xu, T Zhang, M Xu, J Yao, CY Fang… - Journal of …, 2013 - Elsevier
Cystic hydatid disease is an important zoonosis caused by Echinococcus granulosus
infection. The expression profiles of its parasitic life stages and host–Echinococcus …