The role of engineered materials in mucosal vaccination strategies
Mucosal pathogens, as exemplified by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), human immunodeficiency virus (HIV) and Mycobacterium tuberculosis, lead …
(SARS-CoV-2), human immunodeficiency virus (HIV) and Mycobacterium tuberculosis, lead …
[HTML][HTML] The initial interplay between HIV and mucosal innate immunity
V Caputo, M Libera, S Sisti, B Giuliani… - Frontiers in …, 2023 - frontiersin.org
Human Immunodeficiency Virus (HIV) is still one of the major global health issues, and
despite significant efforts that have been put into studying the pathogenesis of HIV infection …
despite significant efforts that have been put into studying the pathogenesis of HIV infection …
[HTML][HTML] From dysbiosis to defense: harnessing the gut microbiome in HIV/SIV therapy
JM Brenchley, S Serrano-Villar - Microbiome, 2024 - Springer
Background Although the microbiota has been extensively associated with HIV
pathogenesis, the majority of studies, particularly those using omics techniques, are largely …
pathogenesis, the majority of studies, particularly those using omics techniques, are largely …
Intestinal Microbiota Dysbiosis Promotes Mucosal Barrier Damage and Immune Injury in HIV‐Infected Patients
Z Pan, N Wu, C Jin - Canadian Journal of Infectious Diseases …, 2023 - Wiley Online Library
The intestinal microbiota is an “invisible organ” in the human body, with diverse components
and complex interactions. Homeostasis of the intestinal microbiota plays a pivotal role in …
and complex interactions. Homeostasis of the intestinal microbiota plays a pivotal role in …
[HTML][HTML] Microbiome studies in non-human primates
JM Brenchley, AM Ortiz - Current HIV/AIDS Reports, 2021 - Springer
Abstract Purpose of Review Observations of differing bacterial, intestinal microbiomes in
people living with HIV have propelled interest in contributions of the microbiome to HIV …
people living with HIV have propelled interest in contributions of the microbiome to HIV …
Coimmunization with Preerythrocytic Antigens alongside Circumsporozoite Protein Can Enhance Sterile Protection against Plasmodium Sporozoite Infection
V Vigdorovich, H Patel, A Watson… - Microbiology …, 2023 - Am Soc Microbiol
Malaria-causing Plasmodium parasites have a complex life cycle and present numerous
antigen targets that may contribute to protective immune responses. The currently …
antigen targets that may contribute to protective immune responses. The currently …
The role of the gut microbiota in regulating responses to vaccination: current knowledge and future directions
C Rossouw, FJ Ryan, DJ Lynn - The FEBS Journal, 2024 - Wiley Online Library
Antigen‐specific B and T cell responses play a critical role in vaccine‐mediated protection
against infectious diseases, but these responses are highly variable between individuals …
against infectious diseases, but these responses are highly variable between individuals …
[HTML][HTML] Untangling the role of the microbiome across the stages of HIV disease
AM Ortiz, JM Brenchley - Current Opinion in HIV and AIDS, 2024 - journals.lww.com
Previous studies considering the role of the microbiome in people living with HIV largely
described viral acquisition as an intrusion on the host: microbiome interface. Re-framing this …
described viral acquisition as an intrusion on the host: microbiome interface. Re-framing this …
Intestinal microbial communities and Holdemanella isolated from HIV+/− men who have sex with men increase frequencies of lamina propria CCR5+ CD4+ T cells
Men who have sex with men (MSM), regardless of HIV infection status, have an intestinal
microbiome that is compositionally distinct from men who have sex with women (MSW) and …
microbiome that is compositionally distinct from men who have sex with women (MSW) and …
Probiotic Therapy During Vaccination Alters Antibody Response to Simian-Human Immunodeficiency Virus Infection But Not to Commensals
The induction of robust circulating antibody titers is a key goal of HIV-1 vaccination. Probiotic
supplementation is an established strategy to enhance microbiota and boost antibody …
supplementation is an established strategy to enhance microbiota and boost antibody …