Spermatogenesis is the cellular process by which spermatogonia develop into mature
spermatids within seminiferous tubules, the functional unit of the mammalian testis, under …

Brain function relies on the ability of neurons to communicate with each other. Interneuronal
communication primarily takes place at synapses, where information from one neuron is …

Endocytic mechanisms control the lipid and protein composition of the plasma membrane,
thereby regulating how cells interact with their environments. Here, we review what is known …

Gap junctions are essential to the function of multicellular animals, which require a high
degree of coordination between cells. In vertebrates, gap junctions comprise connexins and …

Connexins are ubiquitous channel forming proteins that assemble as plasma membrane
hemichannels and as intercellular gap junction channels that directly connect cells. In the …

Gap junctions are aggregates of intercellular channels that permit direct cell–cell transfer of
ions and small molecules. Initially described as low-resistance ion pathways joining …

Gap junctions consist of arrays of intercellular channels that enable adjacent cells to
communicate both electrically and metabolically. Gap junctions have a wide diversity of …

Connexins are chordate gap junction channel proteins that, by enabling direct
communication between the cytosols of adjacent cells, create a unique cell signalling …

Eukaryotic cells constantly form and internalize plasma membrane vesicles in a process
known as endocytosis. Endocytosis serves a variety of housekeeping and specialized …

Gap junctions, composed of proteins from the connexin gene family, are highly dynamic
structures that are regulated by kinase-mediated signaling pathways and interactions with …