[HTML][HTML] Lipid alterations in chronic liver disease and liver cancer
B Paul, M Lewinska, JB Andersen - JHEP reports, 2022 - Elsevier
Lipids are a complex and diverse group of molecules with crucial roles in many
physiological processes, as well as in the onset, progression, and maintenance of cancers …
physiological processes, as well as in the onset, progression, and maintenance of cancers …
Sphingolipids in metabolic disease: The good, the bad, and the unknown
The bioactive sphingolipid metabolites ceramide and sphingosine-1-phosphate (S1P) are a
recent addition to the lipids accumulated in obesity and have emerged as important …
recent addition to the lipids accumulated in obesity and have emerged as important …
[HTML][HTML] Mitochondrial alterations in fatty liver diseases
B Fromenty, M Roden - Journal of hepatology, 2023 - Elsevier
Fatty liver diseases can result from common metabolic diseases, as well as from xenobiotic
exposure and excessive alcohol use, all of which have been shown to exert toxic effects on …
exposure and excessive alcohol use, all of which have been shown to exert toxic effects on …
Understanding NAFLD: from case identification to interventions, outcomes, and future perspectives
D Clayton-Chubb, W Kemp, A Majeed, JS Lubel… - Nutrients, 2023 - mdpi.com
While non-alcoholic fatty liver disease (NAFLD) is a prevalent and frequent cause of liver-
related morbidity and mortality, it is also strongly associated with cardiovascular disease …
related morbidity and mortality, it is also strongly associated with cardiovascular disease …
[HTML][HTML] Non-alcoholic fatty liver disease is characterised by a reduced polyunsaturated fatty acid transport via free fatty acids and high-density lipoproteins (HDL)
G Mocciaro, M Allison, B Jenkins, V Azzu… - Molecular …, 2023 - Elsevier
Background and objectives Non-alcoholic fatty liver disease (NAFLD) develops due to
impaired hepatic lipid fluxes and is a risk factor for chronic liver disease and atherosclerosis …
impaired hepatic lipid fluxes and is a risk factor for chronic liver disease and atherosclerosis …
[HTML][HTML] Recent advances towards mass spectrometry-based clinical lipidomics
S Salihovic, S Lamichane, T Hyötyläinen… - Current opinion in …, 2023 - Elsevier
The objective of this review is to provide a comprehensive summary of the latest
methodological advancements and emerging patterns in utilizing lipidomics in clinical …
methodological advancements and emerging patterns in utilizing lipidomics in clinical …
Lipid profiling identifies modifiable signatures of cardiometabolic risk in children and adolescents with obesity
Pediatric obesity is a progressive, chronic disease that can lead to serious cardiometabolic
complications. Here we investigated the peripheral lipidome in 958 children and …
complications. Here we investigated the peripheral lipidome in 958 children and …
The altered serum lipidome and its diagnostic potential for Non-Alcoholic Fatty Liver (NAFL)-associated hepatocellular carcinoma
M Lewinska, A Santos-Laso, E Arretxe, C Alonso… - …, 2021 - thelancet.com
Background Non-alcoholic fatty liver disease (NAFLD) is affecting more people globally.
Indeed, NAFLD is a spectrum of metabolic dysfunctions that can progress to hepatocellular …
Indeed, NAFLD is a spectrum of metabolic dysfunctions that can progress to hepatocellular …
Serine synthesis via reversed SHMT2 activity drives glycine depletion and acetaminophen hepatotoxicity in MASLD
A Ghrayeb, AC Finney, B Agranovich, D Peled… - Cell Metabolism, 2024 - cell.com
Metabolic dysfunction-associated steatotic liver disease (MASLD) affects one-third of the
global population. Understanding the metabolic pathways involved can provide insights into …
global population. Understanding the metabolic pathways involved can provide insights into …
Quantification of lipid droplets polarity for evaluating non-alcoholic fatty liver disease via fluorescence lifetime imaging
C Lai, Y Zhao, X Zou, Y Liang, W Lin - Sensors and Actuators B: Chemical, 2022 - Elsevier
Lipid droplets (LDs) are a kind of subcellular organelle, and LDs' polarity is closely
associated with the initiation and development of non-alcoholic fatty liver disease (NAFLD) …
associated with the initiation and development of non-alcoholic fatty liver disease (NAFLD) …