Psychopharmacological advances in eating disorders

H Himmerich, J Treasure - Expert review of clinical pharmacology, 2018 - Taylor & Francis
ABSTRACT Introduction: Anorexia nervosa (AN), bulimia nervosa (BN) and binge eating
disorder (BED) are the primary eating disorders (EDs). The only psychopharmacological …

An evolutionary genetic perspective of eating disorders

AJ Mayhew, M Pigeyre, J Couturier, D Meyre - Neuroendocrinology, 2018 - karger.com
Eating disorders (ED) including anorexia nervosa (AN), bulimia nervosa (BN), and binge
eating disorder (BED) affect up to 5% of the population in Western countries. Risk factors for …

Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

A Hinney, M Kesselmeier, S Jall, AL Volckmar… - Molecular …, 2017 - nature.com
The maintenance of normal body weight is disrupted in patients with anorexia nervosa (AN)
for prolonged periods of time. Prior to the onset of AN, premorbid body mass index (BMI) …

Genetic variants in dopamine pathways affect personality dimensions displayed by patients with eating disorders

LM González, S Mota-Zamorano… - Eating and Weight …, 2021 - Springer
Purpose We aimed to analyze the association between common polymorphisms in
dopamine pathways with personality dimensions frequently present in patients with eating …

Variability in cannabinoid receptor genes is associated with psychiatric comorbidities in anorexia nervosa

LM González, A García-Herráiz… - Eating and Weight …, 2021 - Springer
Purpose The endocannabinoid system plays a key role in eating behavior regulating
appetite and reward mechanisms, but the impact of its genetic variability has been scarcely …

The association between polymorphisms near TMEM18 and the risk of obesity: a meta-analysis

N Koj, Ł Grochowalski, J Jarczak, W Wójtowicz… - BMC Medical …, 2021 - Springer
Background Many studies have proposed that the pathogenesis of obesity has a genetic
basis, with an important risk factor being the presence of polymorphisms in the region of the …

Influence of TFAP2B and KCTD15 genetic variability on personality dimensions in anorexia and bulimia nervosa

C Gamero‐Villarroel, LM González… - Brain and …, 2017 - Wiley Online Library
Abstract Introduction TFAP 2B and KCTD 15 are obesity‐related genes that interact to
regulate feeding behavior. We hypothesize that variability in these loci, isolated or in …

CRISPR/Cas9, the powerful new genome-editing tool for putative therapeutics in obesity

MJ Franco-Tormo, M Salas-Crisostomo… - Journal of Molecular …, 2018 - Springer
The molecular technology known as c lustered r egularly i nter s paced p alindromic r epeats
(CRISPR)/CRISPR-associated protein (Cas) is revolutionizing the field of medical research …

Variants in the Obesity-Linked FTO gene locus modulates psychopathological features of patients with Anorexia Nervosa

LM González, A García-Herráiz, S Mota-Zamorano… - Gene, 2021 - Elsevier
Our aim was to determine whether variability in the fat mass obesity (FTO) gene locus,
consistently related to obesity, affects the risk of eating disorders (ED) and/or the …

[HTML][HTML] Associations of two obesity-related single-nucleotide polymorphisms with adiponectin in Chinese children

L Wu, L Gao, X Zhao, M Zhang, J Wu, J Mi - International journal of …, 2017 - hindawi.com
Purpose. Genome-wide association studies have found two obesity-related single-
nucleotide polymorphisms (SNPs), rs17782313 near the melanocortin-4 receptor (MC4R) …