Mephedrone and MDMA are both constituents of party drugs, with mephedrone being
relatively new compared to MDMA. This review compares current knowledge regarding the …

Abstract±3, 4-Methylenedioxymethamphetamine (MDMA) is a synthetic, psychoactive drug
that is primarily used recreationally but also may have some therapeutic value. At low doses …

Abstract Cyclin-dependent kinase 5 (Cdk5)/p35 is involved in many developmental
processes of the central nervous system. Cdk5/p35 is also implicated in synaptic plasticity …

Brain trauma triggers a cascade of deleterious events leading to enhanced incidence of
drug resistant epilepsies, depression, and cognitive dysfunctions. The underlying …

Psychoactive substances are a class of chemical substances which could cause public
health threats. Cognitive disorders are a category of mental health disorders that primarily …

Exposure to social stress alters the response to drugs of abuse of experimental animals.
Changes in the glutamatergic system seem to play a role in the effects of social defeat stress …

Methylenedioxymethamphetamine (MDMA,“Ecstasy”) use has been linked to persistent
alterations of the brain serotonergic (5-HT) system in animal and human studies, but the …

Abstract MDMA (3, 4-methylendioxymethamphetamine), also known as Ecstasy, is a
stimulant drug recreationally used by young adults usually in dance clubs and raves. Acute …

We have previously observed that mice exposed to social defeat stress are more sensitive to
cocaine in the conditioned place preference (CPP) paradigm. In this context, it has been …

Introduction Drug addiction continues being a major public problem faced by modern
societies with different social, health and legal consequences for the consumers …