Despite recent successful efforts to reduce the global malaria burden, this disease remains a
significant global health problem. Only in 2018, malaria caused 228 million clinical …

Malaria affected an estimated 216 million people causing 445,000 deaths in 2016. 1 This
reduced burden of disease and death is a result of more than a century of worldwide effort …

Acute kidney injury (AKI) is emerging as a complication of increasing clinical importance
associated with substantial morbidity and mortality in African children with severe malaria …

Background Despite recent efforts and successes in reducing the malaria burden globally,
this infection still accounts for an estimated 212 million clinical cases, 2 million severe …

Background Acute kidney injury (AKI) is a recognized complication of pediatric severe
malaria, but its long-term consequences are unknown. Methods Ugandan children with …

Acute kidney injury (AKI) is a common feature of severe malaria, and an independent risk
factor for death. Previous research has suggested that an overactivation of the host …

Introduction. Cerebral malaria is one of the most severe manifestations of malaria and is a
leading cause of acquired neurodisability in African children. Recent studies suggest acute …

Background Mortality in severe malaria remains high in children treated with intravenous
artesunate. Acute kidney injury (AKI) is a common complication of severe malaria, but the …

Background Acute kidney injury independently predicts mortality in falciparum malaria. It is
unknown whether acetaminophen's capacity to inhibit plasma hemoglobin-mediated …

Over the past 15 years, malaria mortality has reduced by approximately 50%. However,
malaria still causes more than 400,000 deaths annually, most of which occur in African …