Regulation of the master regulator FOXM1 in cancer
GB Liao, XZ Li, S Zeng, C Liu, SM Yang, L Yang… - Cell Communication and …, 2018 - Springer
FOXM1 (forkhead box protein M1) is a critical proliferation-associated transcription factor
that is widely spatiotemporally expressed during the cell cycle. It is closely involved with the …
that is widely spatiotemporally expressed during the cell cycle. It is closely involved with the …
Forkhead box proteins: tuning forks for transcriptional harmony
EWF Lam, JJ Brosens, AR Gomes, CY Koo - Nature Reviews Cancer, 2013 - nature.com
Forkhead box (FOX) proteins are multifaceted transcription factors that are responsible for
fine-tuning the spatial and temporal expression of a broad range of genes both during …
fine-tuning the spatial and temporal expression of a broad range of genes both during …
FOXM1 and cancer: faulty cellular signaling derails homeostasis
D Kalathil, S John, AS Nair - Frontiers in oncology, 2021 - frontiersin.org
Forkhead box transcription factor, FOXM1 is implicated in several cellular processes such as
proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue …
proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue …
[HTML][HTML] FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis
Wnt/β-catenin signaling is essential for stem cell regulation and tumorigenesis, but its
molecular mechanisms are not fully understood. Here, we report that FoxM1 is a …
molecular mechanisms are not fully understood. Here, we report that FoxM1 is a …
Pan-cancer analyses reveal genomic features of FOXM1 overexpression in cancer
FOXM1 is frequently overexpressed in cancer, but this has not been studied in a
comprehensive manner. We utilized genotype-tissue expression (GTEx) normal and The …
comprehensive manner. We utilized genotype-tissue expression (GTEx) normal and The …
Regulation of dual-specificity phosphatase (DUSP) ubiquitination and protein stability
HF Chen, HC Chuang, TH Tan - International journal of molecular …, 2019 - mdpi.com
Mitogen-activated protein kinases (MAPKs) are key regulators of signal transduction and cell
responses. Abnormalities in MAPKs are associated with multiple diseases. Dual-specificity …
responses. Abnormalities in MAPKs are associated with multiple diseases. Dual-specificity …
The emerging roles of forkhead box (Fox) proteins in cancer
SS Myatt, EWF Lam - Nature Reviews Cancer, 2007 - nature.com
Forkhead box (Fox) proteins are a superfamily of evolutionarily conserved transcriptional
regulators, which control a wide spectrum of biological processes. As a consequence, a loss …
regulators, which control a wide spectrum of biological processes. As a consequence, a loss …
Cancer genetics and genomics of human FOX family genes
M Katoh, M Igarashi, H Fukuda, H Nakagama, M Katoh - Cancer letters, 2013 - Elsevier
Forkhead-box (FOX) family proteins, involved in cell growth and differentiation as well as
embryogenesis and longevity, are DNA-binding proteins regulating transcription and DNA …
embryogenesis and longevity, are DNA-binding proteins regulating transcription and DNA …
FOXM1: From cancer initiation to progression and treatment
The Forkhead box protein M1 (FOXM1) transcription factor is a regulator of myriad biological
processes, including cell proliferation, cell cycle progression, cell differentiation, DNA …
processes, including cell proliferation, cell cycle progression, cell differentiation, DNA …
Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1
SA Caldwell, SR Jackson, KS Shahriari, TP Lynch… - Oncogene, 2010 - nature.com
Cancer cells upregulate glycolysis, increasing glucose uptake to meet energy needs. A
small fraction of a cell's glucose enters the hexosamine biosynthetic pathway (HBP), which …
small fraction of a cell's glucose enters the hexosamine biosynthetic pathway (HBP), which …