Biocontrol yeasts: mechanisms and applications

FM Freimoser, MP Rueda-Mejia, B Tilocca… - World Journal of …, 2019 - Springer
Yeasts occur in all environments and have been described as potent antagonists of various
plant pathogens. Due to their antagonistic ability, undemanding cultivation requirements …

Recent advances in systems and synthetic biology approaches for developing novel cell-factories in non-conventional yeasts

P Patra, M Das, P Kundu, A Ghosh - Biotechnology Advances, 2021 - Elsevier
Microbial bioproduction of chemicals, proteins, and primary metabolites from cheap carbon
sources is currently an advancing area in industrial research. The model yeast …

Recent advances in metabolic engineering of Saccharomyces cerevisiae: new tools and their applications

J Lian, S Mishra, H Zhao - Metabolic engineering, 2018 - Elsevier
Metabolic engineering aims to develop efficient cell factories by rewiring cellular
metabolism. As one of the most commonly used cell factories, Saccharomyces cerevisiae …

CRISPR-mediated genome editing in non-conventional yeasts for biotechnological applications

P Cai, J Gao, Y Zhou - Microbial cell factories, 2019 - Springer
Non-conventional yeasts are playing important roles as cell factories for bioproduction of
biofuels, food additives and proteins with outstanding natural characteristics. However, the …

Stress-tolerant non-conventional microbes enable next-generation chemical biosynthesis

S Thorwall, C Schwartz, JW Chartron… - Nature chemical …, 2020 - nature.com
Microbial chemical production is a rapidly growing industry, with much of the growth fueled
by advances in synthetic biology. New approaches have enabled rapid strain engineering …

[HTML][HTML] Genome and metabolic engineering in non-conventional yeasts: current advances and applications

AK Löbs, C Schwartz, I Wheeldon - Synthetic and systems biotechnology, 2017 - Elsevier
Microbial production of chemicals and proteins from biomass-derived and waste sugar
streams is a rapidly growing area of research and development. While the model yeast …

Recombination machinery engineering for precise genome editing in methylotrophic yeast Ogataea polymorpha

J Gao, N Gao, X Zhai, YJ Zhou - Iscience, 2021 - cell.com
Methanol biotransformation can expand biorefinery substrate spectrum other than biomass
by using methylotrophic microbes. Ogataea (Hansenula) polymorpha, a representative …

Xylose and shikimate transporters facilitates microbial consortium as a chassis for benzylisoquinoline alkaloid production

M Gao, Y Zhao, Z Yao, Q Su, P Van Beek… - Nature …, 2023 - nature.com
Plant-sourced aromatic amino acid (AAA) derivatives are a vast group of compounds with
broad applications. Here, we present the development of a yeast consortium for efficient …

A repackaged CRISPR platform increases homology-directed repair for yeast engineering

D Ploessl, Y Zhao, M Cao, S Ghosh, C Lopez… - Nature Chemical …, 2022 - nature.com
Inefficient homology-directed repair (HDR) constrains CRISPR–Cas9 genome editing in
organisms that preferentially employ nonhomologous end joining (NHEJ) to fix DNA double …

Development and application of CRISPR/Cas in microbial biotechnology

W Ding, Y Zhang, S Shi - Frontiers in Bioengineering and …, 2020 - frontiersin.org
The clustered regularly interspaced short palindromic repeats (CRISPR)-associated (Cas)
system has been rapidly developed as versatile genomic engineering tools with high …