Circulation. 2017; 136: 680–686. DOI: 10.1161/CIRCULATIONAHA. 117.029343 August 15,
2017 681 proliferation. 5 It remains unclear whether this regenerative window exists in large …

Ischaemic heart disease is a leading cause of death worldwide. Injury to the heart is
followed by loss of the damaged cardiomyocytes, which are replaced with fibrotic scar …

Pluripotent stem cell–derived cardiomyocyte grafts can remuscularize substantial amounts
of infarcted myocardium and beat in synchrony with the heart, but in some settings cause …

Induced pluripotent stem cells (iPSCs) constitute a potential source of autologous patient-
specific cardiomyocytes for cardiac repair, providing a major benefit over other sources of …

Human cardiac organoids hold remarkable potential for cardiovascular disease modeling
and human pluripotent stem cell–derived cardiomyocyte (hPSC-CM) transplantation. Here …

The myocardium behaves like a sophisticated orchestra that expresses its true potential only
if each member performs the correct task harmonically. Recapitulating its complexity within …

Magnetic microrobots were developed for three-dimensional culture and the precise delivery
of stem cells in vitro, ex vivo, and in vivo. Hippocampal neural stem cells attached to the …

The generation of insulin-producing pancreatic β cells from stem cells in vitro would provide
an unprecedented cell source for drug discovery and cell transplantation therapy in …

Exploring innovative solutions to improve the healthcare of the aging and diseased
population continues to be a global challenge. Among a number of strategies toward this …

Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) show considerable
promise for regenerating injured hearts, and we therefore tested their capacity to stably …