In this perspective article, we reflect on the recent debate about the existence of human
neurogenesis and discuss direct, and also indirect, support for the ongoing formation, and …

The mammalian brain relies on neurochemistry to fulfill its functions. Yet, the complexity of
the brain metabolome and its changes during diseases or aging remain poorly understood …

In this systematic review, we highlight the differences between the male and female
zebrafish brains to understand their differentiation and their use in studying sex-specific …

Calorie restriction (CR) or a fasting regimen is considered one of the most potent non-
pharmacological interventions to prevent chronic metabolic disorders, ameliorate …

Selenium (Se) is a trace element crucial for human health. Recently, the impact of Se
supplementation on gut microbiota has been pointed out as well as its influence on the …

Sleep has evolved as a universal core function to allow for restorative biological processes.
Detailed knowledge of metabolic changes necessary for the sleep state in the brain is …

Acylcarnitines and amino acids are key players in energy metabolism; however, analytical
methods for comprehensive and straightforward quantitative profiling of these metabolites …

Background Late‐onset depression (LOD) is defined as primary depression that first
manifests after the age of 65. Luteolin (LUT) is a natural flavonoid that has shown promising …

Neurodegenerative diseases are prevalent and devastating. While extensive research has
been done over the past decades, we are still far from comprehensively understanding what …

Frontotemporal dementia (FTD) is a heterogeneous neurodegenerative disease with
multiple histopathological subtypes. FTD patients share similar symptoms with Alzheimer's …