Bioengineering virus‐like particles as vaccines
LHL Lua, NK Connors, F Sainsbury… - Biotechnology and …, 2014 - Wiley Online Library
Virus‐like particle (VLP) technology seeks to harness the optimally tuned immunostimulatory
properties of natural viruses while omitting the infectious trait. VLPs that assemble from a …
properties of natural viruses while omitting the infectious trait. VLPs that assemble from a …
Platforms, advances, and technical challenges in virus-like particles-based vaccines
R Gupta, K Arora, SS Roy, A Joseph… - Frontiers in …, 2023 - frontiersin.org
Viral infectious diseases threaten human health and global stability. Several vaccine
platforms, such as DNA, mRNA, recombinant viral vectors, and virus-like particle-based …
platforms, such as DNA, mRNA, recombinant viral vectors, and virus-like particle-based …
Synthetic biology for bioengineering virus‐like particle vaccines
HK Charlton Hume, J Vidigal… - Biotechnology and …, 2019 - Wiley Online Library
Vaccination is the most effective method of disease prevention and control. Many viruses
and bacteria that once caused catastrophic pandemics (eg, smallpox, poliomyelitis …
and bacteria that once caused catastrophic pandemics (eg, smallpox, poliomyelitis …
Complete and cooperative in vitro assembly of computationally designed self-assembling protein nanomaterials
AJ Wargacki, TP Wörner, M van de Waterbeemd… - Nature …, 2021 - nature.com
Recent advances in computational methods have enabled the predictive design of self-
assembling protein nanomaterials with atomic-level accuracy. These design strategies focus …
assembling protein nanomaterials with atomic-level accuracy. These design strategies focus …
Next generation vaccines and vectors: Designing downstream processes for recombinant protein‐based virus‐like particles
In recent years, the development of novel recombinant virus‐like particles (VLPs) has been
generating new perspectives for the prevention of untreated and arising infectious diseases …
generating new perspectives for the prevention of untreated and arising infectious diseases …
Exploiting virus-like particles as innovative vaccines against emerging viral infections
Emerging viruses pose a major threat to humans and livestock with global public health and
economic burdens. Vaccination remains an effective tool to reduce this threat, and yet, the …
economic burdens. Vaccination remains an effective tool to reduce this threat, and yet, the …
Virus-like particles: the future of microbial factories and cell-free systems as platforms for vaccine development
Highlights▶ Microorganisms are inexpensive platforms to produce chimeric VLPs.▶
Bacteriophage-derived VLPs are excellent structures for drug delivery.▶ Microbial cell …
Bacteriophage-derived VLPs are excellent structures for drug delivery.▶ Microbial cell …
Insect cells as a production platform of complex virus-like particles
F Fernandes, AP Teixeira, N Carinhas… - Expert review of …, 2013 - Taylor & Francis
Virus-like particles (VLPs) are multiprotein structures that resemble the conformation of
native viruses but lack a viral genome, potentiating their application as safer and cheaper …
native viruses but lack a viral genome, potentiating their application as safer and cheaper …
Plant viruses in plant molecular pharming: toward the use of enveloped viruses
A Ibrahim, V Odon, R Kormelink - Frontiers in Plant Science, 2019 - frontiersin.org
Plant molecular pharming has emerged as a reliable platform for recombinant protein
expression providing a safe and low-cost alternative to bacterial and mammalian cells …
expression providing a safe and low-cost alternative to bacterial and mammalian cells …
Advances in virus-like particle-based SARS-CoV-2 vaccines
X Hao, F Yuan, X Yao - Frontiers in Cellular and Infection …, 2024 - frontiersin.org
The Coronavirus Disease 2019 (COVID-19) pandemic, caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has incurred devastating human and …
respiratory syndrome coronavirus 2 (SARS-CoV-2), has incurred devastating human and …