Fluorescent probe strategy for live cell distinction

X Liu, YT Chang - Chemical Society Reviews, 2022 - pubs.rsc.org
Live cell discrimination is the first and essential step to understand complex biosystems.
Conventional cell discrimination involving various antibodies relies on selective surface …

Bright building blocks for chemical biology

LD Lavis, RT Raines - ACS chemical biology, 2014 - ACS Publications
Small-molecule fluorophores manifest the ability of chemistry to solve problems in biology.
As we noted in a previous review (Lavis, LD; Raines, RT ACS Chem. Biol. 2008, 3, 142 …

Combinatorial strategies in fluorescent probe development

M Vendrell, D Zhai, JC Er, YT Chang - Chemical reviews, 2012 - ACS Publications
The need for understanding essential recognition events in chemistry and biology has
directed considerable efforts toward the development of chemical probes. Fluorescent …

Teaching old dyes new tricks: biological probes built from fluoresceins and rhodamines

LD Lavis - Annual review of biochemistry, 2017 - annualreviews.org
Small-molecule fluorophores, such as fluorescein and rhodamine derivatives, are critical
tools in modern biochemical and biological research. The field of chemical dyes is old; …

Small-molecule fluorophores and fluorescent probes for bioimaging

T Terai, T Nagano - Pflügers Archiv-European Journal of Physiology, 2013 - Springer
Fluorescent compounds based on synthetic small molecules are powerful tools to visualize
biological events in living cells and organisms. Ever since the discovery of organic …

Advances in the chemistry of small molecule fluorescent probes

LM Wysocki, LD Lavis - Current opinion in chemical biology, 2011 - Elsevier
Small molecule fluorophores are essential tools for chemical biology. A benefit of synthetic
dyes is the ability to employ chemical approaches to control the properties and direct the …

Chemical fluorescent probe for detection of Aβ oligomers

CL Teoh, D Su, S Sahu, SW Yun… - Journal of the …, 2015 - ACS Publications
Aggregation of amyloid β-peptide (Aβ) is implicated in the pathology of Alzheimer's disease
(AD), with the soluble, Aβ oligomeric species thought to be the critical pathological species …

Emission Wavelength Prediction of a Full-Color-Tunable Fluorescent Core Skeleton, 9-Aryl-1,2-dihydropyrrolo[3,4-b]indolizin-3-one

E Kim, M Koh, BJ Lim, SB Park - Journal of the American Chemical …, 2011 - ACS Publications
In this paper we report on a novel fluorescent core skeleton, 9-aryl-1, 2-dihydropyrrolo [3, 4-
b] indolizin-3-one, which we named Seoul-Fluor, having tunable and predictable …

Diversity oriented fluorescence library approach (DOFLA) for live cell imaging probe development

SW Yun, NY Kang, SJ Park, HH Ha… - Accounts of chemical …, 2014 - ACS Publications
A cell is the smallest functional unit of life. All forms of life rely on cellular processes to
maintain normal functions, and changes in cell function induced by metabolic disturbances …

Chronological development of functional fluorophores for bio-imaging

S Munan, YT Chang, A Samanta - Chemical Communications, 2023 - pubs.rsc.org
Functional fluorophores represent an emerging research field, distinguished by their diverse
applications, especially in sensing and cellular imaging. After the discovery of Quinine …