High-Resolution Transcriptome Maps Reveal Strain-Specific Regulatory Features of Multiple Campylobacter jejuni Isolates
Campylobacter jejuni is currently the leading cause of bacterial gastroenteritis in humans.
Comparison of multiple Campylobacter strains revealed a high genetic and phenotypic …
Comparison of multiple Campylobacter strains revealed a high genetic and phenotypic …
Regulation of transcription by eukaryotic-like serine-threonine kinases and phosphatases in Gram-positive bacterial pathogens
DP Wright, AT Ulijasz - Virulence, 2014 - Taylor & Francis
Bacterial eukaryotic-like serine threonine kinases (eSTKs) and serine threonine
phosphatases (eSTPs) have emerged as important signaling elements that are …
phosphatases (eSTPs) have emerged as important signaling elements that are …
Dual-site phosphorylation of the control of virulence regulator impacts group a streptococcal global gene expression and pathogenesis
N Horstmann, M Saldaña, P Sahasrabhojane… - PLoS …, 2014 - journals.plos.org
Phosphorylation relays are a major mechanism by which bacteria alter transcription in
response to environmental signals, but understanding of the functional consequences of …
response to environmental signals, but understanding of the functional consequences of …
[HTML][HTML] Streptococcus pyogenes genomics
F Maruyama, T Watanabe, I Nakagawa - 2016 - europepmc.org
Outbreaks of epidemic infections by Streptococcus pyogenes, the group A streptococci, have
been known for centuries to be a major cause of substantial human morbidity and mortality …
been known for centuries to be a major cause of substantial human morbidity and mortality …
CovS inactivation reduces CovR promoter binding at diverse virulence factor encoding genes in group A Streptococcus
The c ontrol ofv irulence gene r egulator (CovR), also called c aspsule s ynthesis r egulator
(CsrR), is critical to how the major human pathogen group A Streptococcus fine-tunes …
(CsrR), is critical to how the major human pathogen group A Streptococcus fine-tunes …
Transcriptome remodeling contributes to epidemic disease caused by the human pathogen Streptococcus pyogenes
For over a century, a fundamental objective in infection biology research has been to
understand the molecular processes contributing to the origin and perpetuation of …
understand the molecular processes contributing to the origin and perpetuation of …
Phosphatase activity of the control of virulence sensor kinase CovS is critical for the pathogenesis of group A streptococcus
N Horstmann, CN Tran, C Brumlow, S DebRoy… - PLoS …, 2018 - journals.plos.org
The control of virulence regulator/sensor kinase (CovRS) two-component system is critical to
the infectivity of group A streptococcus (GAS), and CovRS inactivating mutations are …
the infectivity of group A streptococcus (GAS), and CovRS inactivating mutations are …
The Abi-domain Protein Abx1 Interacts with the CovS Histidine Kinase to Control Virulence Gene Expression in Group B Streptococcus
A Firon, A Tazi, V Da Cunha, S Brinster… - PLoS …, 2013 - journals.plos.org
Group B Streptococcus (GBS), a common commensal of the female genital tract, is the
leading cause of invasive infections in neonates. Expression of major GBS virulence factors …
leading cause of invasive infections in neonates. Expression of major GBS virulence factors …
Characterization of the effect of the histidine kinase CovS on response regulator phosphorylation in group A Streptococcus
N Horstmann, P Sahasrabhojane, M Saldaña… - Infection and …, 2015 - Am Soc Microbiol
Two-component gene regulatory systems (TCSs) are a major mechanism by which bacteria
respond to environmental stimuli and thus are critical to infectivity. For example, the c ontrol …
respond to environmental stimuli and thus are critical to infectivity. For example, the c ontrol …
A novel CovS variant harbored by a colonization strain reduces Streptococcus pyogenes virulence
C Plainvert, I Rosinski-Chupin, A Weckel… - Journal of …, 2023 - Am Soc Microbiol
Streptococcus pyogenes, also known as group A Streptococcus, causes a wide variety of
diseases ranging from mild noninvasive to severe invasive infections. To identify possible …
diseases ranging from mild noninvasive to severe invasive infections. To identify possible …