Physiological rhythms and biological variation of biomolecules: the road to personalized laboratory medicine

A Coskun, A Zarepour, A Zarrabi - International journal of molecular …, 2023 - mdpi.com
The concentration of biomolecules in living systems shows numerous systematic and
random variations. Systematic variations can be classified based on the frequency of …

Laboratory measurement of growth hormone

V Popii, G Baumann - Clinica Chimica Acta, 2004 - Elsevier
Growth hormone (GH) measurements are complicated by the heterogeneous nature of GH,
as well as by the presence of the GH binding protein in plasma. Several isoforms of GH …

Model of normal prepubertal growth.

NK Thalange, PJ Foster, MS Gill, DA Price… - Archives of disease in …, 1996 - adc.bmj.com
Growth over the short term is a highly complex non-linear process. Contrasting models of
short term growth have been proposed which include periodic growth cycles versus abrupt …

[HTML][HTML] The relationship between stature, growth, and short-term changes in height and weight in normal prepubertal children

V Tillmann, NKS Thalange, PJ Foster, MS Gill… - Pediatric …, 1998 - nature.com
Human growth is a nonlinear process with marked variation in growth rate during the short-
term. It is not known how long-term height gain or stature is influenced by short-term …

[HTML][HTML] Transcriptomics and machine learning predict diagnosis and severity of growth hormone deficiency

PG Murray, A Stevens, C De Leonibus, E Koledova… - JCI insight, 2018 - ncbi.nlm.nih.gov
BACKGROUND. The effect of gene expression data on diagnosis remains limited. Here, we
show how diagnosis and classification of growth hormone deficiency (GHD) can be …

Correlations of growth hormone (GH) and insulin-like growth factor I (IGF-I): effects of exercise and abuse by athletes

EF De Palo, R Gatti, F Lancerin, E Cappellin… - Clinica chimica acta, 2001 - Elsevier
The importance of hormones on body metabolism when physical exercise is carried out has
been established for a long time. Growth hormone (GH) is crucial in energy metabolism as …

Urinary GH and IGF‐I excretion in nine year‐old children: relation to sex, current size and size at birth

CHD Fall, PM Clark, PC Hindmarsh… - Clinical …, 2000 - Wiley Online Library
OBJECTIVES To study the relationship of 24‐hour urinary growth hormone (GH) and IGF‐I
excretion in childhood to sex and body size. To test the hypothesis that small size at birth …

Patterns of GH output and their synchrony with short-term height increments influence stature and growth performance in normal children

MS Gill, V Tillmann, JD Veldhuis… - The Journal of Clinical …, 2001 - academic.oup.com
GH is the principal hormone driving growth throughout childhood, but the mechanism by
which changing GH secretion is translated into height (Ht) remains undefined. We previously …

Reduced foetal growth and growth hormone secretion in adult life

DE Flanagan, VM Moore, IF Godsland… - Clinical …, 1999 - Wiley Online Library
OBJECTIVES Recent studies suggest that growth restriction or other adverse influences
acting in utero or during early infancy lead to permanent alterations in growth hormone (GH) …

Normal and disordered growth

L Patel, PE Clayton - Clinical pediatric endocrinology, 2005 - Wiley Online Library
Growth can be defined as a process of increase in size by accretion of tissue. It is observed
in the whole organism, in body regions, in organ systems, and in the cellular environment. It …