Mesoporous silica and organosilica nanoparticles: physical chemistry, biosafety, delivery strategies, and biomedical applications

JG Croissant, Y Fatieiev, A Almalik… - Advanced healthcare …, 2018 - Wiley Online Library
Predetermining the physico‐chemical properties, biosafety, and stimuli‐responsiveness of
nanomaterials in biological environments is essential for safe and effective biomedical …

Advanced nitric oxide donors: Chemical structure of NO drugs, NO nanomedicines and biomedical applications

Y Yang, Z Huang, LL Li - Nanoscale, 2021 - pubs.rsc.org
Nitric oxide (NO), as an endogenous diatomic molecule, plays a key regulatory role in many
physiological and pathological processes. This diatomic free radical has been shown to …

Antibacterial dental composites with chlorhexidine and mesoporous silica

JF Zhang, R Wu, Y Fan, S Liao… - Journal of dental …, 2014 - journals.sagepub.com
One of the leading causes for the failure of dental composite restorations is secondary
caries. Effectively inhibiting cariogenic biofilms and reducing secondary caries could extend …

Delivering nitric oxide with nanoparticles

JF Quinn, MR Whittaker, TP Davis - Journal of controlled release, 2015 - Elsevier
While best known for its important signalling functions in human physiology, nitric oxide is
also of considerable therapeutic interest. As such, nanoparticle-based systems which …

A platform for nitric oxide delivery

J Kim, G Saravanakumar, HW Choi, D Park… - Journal of Materials …, 2014 - pubs.rsc.org
Nitric oxide (NO) is one of the structurally smallest pharmaceutical molecules, which shows
great potential as an anti-restenosis, wound healing, anticancer, and antibacterial agent. To …

Opportunities for nitric oxide in potentiating cancer immunotherapy

J Kim, SN Thomas, M Michel - Pharmacological Reviews, 2022 - Elsevier
Despite nearly 30 years of development and recent highlights of nitric oxide (NO) donors
and NO delivery systems in anticancer therapy, the limited understanding of exogenous …

Antimicrobial polymers in the nano-world

M Álvarez-Paino, A Muñoz-Bonilla… - Nanomaterials, 2017 - mdpi.com
Infections are one of the main concerns of our era due to antibiotic-resistant infections and
the increasing costs in the health-care sector. Within this context, antimicrobial polymers …

Dual action nitric oxide and fluoride ion-releasing hydrogels for combating dental caries

LM Estes Bright, MRS Garren, M Ashcraft… - … applied materials & …, 2022 - ACS Publications
Demineralization and breakdown of tooth enamel are characterized by a condition called
dental caries or tooth decay, which is caused by two main factors:(1) highly acidic food …

Bacteria-adhesive nitric oxide-releasing graphene oxide nanoparticles for MRPA-infected wound healing therapy

J Cao, SP Hlaing, J Lee, J Kim, EH Lee… - … Applied Materials & …, 2022 - ACS Publications
A bacteria-infected wound can lead to being life-threatening and raises a great economic
burden on the patient. Here, we developed polyethylenimine 1.8 k (PEI1. 8k) surface …

Drug self-assembly for synthesis of highly-loaded antimicrobial drug-silica particles

CA Stewart, Y Finer, BD Hatton - Scientific reports, 2018 - nature.com
Antimicrobial drug release from biomaterials for orthopedic repair and dental restorations
can prevent biofilm growth and caries formation. Carriers for drug incorporation would …