[HTML][HTML] PI3K/AKT signal pathway: a target of natural products in the prevention and treatment of Alzheimer's disease and Parkinson's disease
HZ Long, Y Cheng, ZW Zhou, HY Luo… - Frontiers in …, 2021 - frontiersin.org
Alzheimer's disease (AD) and Parkinson's disease (PD) are two typical neurodegenerative
diseases that increased with aging. With the emergence of aging population, the health …
diseases that increased with aging. With the emergence of aging population, the health …
The dialogue between neuroinflammation and adult neurogenesis: mechanisms involved and alterations in neurological diseases
Adult neurogenesis occurs mainly in the subgranular zone of the hippocampal dentate gyrus
and the subventricular zone of the lateral ventricles. Evidence supports the critical role of …
and the subventricular zone of the lateral ventricles. Evidence supports the critical role of …
Neuroinflammation in neurological disorders: pharmacotherapeutic targets from bench to bedside
Neuroinflammation is one of the host defensive mechanisms through which the nervous
system protects itself from pathogenic and or infectious insults. Moreover, neuroinflammation …
system protects itself from pathogenic and or infectious insults. Moreover, neuroinflammation …
[HTML][HTML] The effect of curcumin on cognition in Alzheimer's disease and healthy aging: A systematic review of pre-clinical and clinical studies
SD Voulgaropoulou, T Van Amelsvoort, J Prickaerts… - Brain research, 2019 - Elsevier
Alzheimer's disease constitutes a growing cause of cognitive impairment in aging
population. Given that current treatments do not produce the desired therapeutic effects, the …
population. Given that current treatments do not produce the desired therapeutic effects, the …
[HTML][HTML] Neuroinflammation and neurogenesis in Alzheimer's disease and potential therapeutic approaches
PS Sung, PY Lin, CH Liu, HC Su, KJ Tsai - International journal of …, 2020 - mdpi.com
In adult brain, new neurons are generated throughout adulthood in the subventricular zone
and the dentate gyrus; this process is commonly known as adult neurogenesis. The …
and the dentate gyrus; this process is commonly known as adult neurogenesis. The …
[HTML][HTML] Curcumin, hormesis and the nervous system
M Concetta Scuto, C Mancuso, B Tomasello… - Nutrients, 2019 - mdpi.com
Curcumin is a polyphenol compound extracted from the rhizome of Curcuma longa Linn
(family Zingiberaceae) commonly used as a spice to color and flavor food. Several …
(family Zingiberaceae) commonly used as a spice to color and flavor food. Several …
Neuroprotective effects of curcumin in cerebral ischemia: cellular and molecular mechanisms
Despite being a major global health concern, cerebral ischemia/stroke has limited
therapeutic options. Tissue plasminogen activator (tPA) is the only available medication to …
therapeutic options. Tissue plasminogen activator (tPA) is the only available medication to …
[HTML][HTML] The emerging role of curcumin in the modulation of TLR-4 signaling pathway: focus on neuroprotective and anti-rheumatic properties
MA Panaro, A Corrado, T Benameur, CF Paolo… - International Journal of …, 2020 - mdpi.com
Natural products have been used in medicine for thousands of years. Given their potential
health benefits, they have gained significant popularity in recent times. The administration of …
health benefits, they have gained significant popularity in recent times. The administration of …
[HTML][HTML] Analogous β-carboline alkaloids harmaline and harmine ameliorate scopolamine-induced cognition dysfunction by attenuating acetylcholinesterase activity …
SP Li, YW Wang, SL Qi, YP Zhang, G Deng… - Frontiers in …, 2018 - frontiersin.org
The analogous β-carboline alkaloids, harmaline (HAL) and harmine (HAR), possess a
variety of biological properties, including acetylcholinesterase (AChE) inhibitory activity …
variety of biological properties, including acetylcholinesterase (AChE) inhibitory activity …
[HTML][HTML] Novel therapeutic delivery of nanocurcumin in central nervous system related disorders
Nutraceuticals represent complementary or alternative beneficial products to the expensive
and high-tech therapeutic tools in modern medicine. Nowadays, their medical or health …
and high-tech therapeutic tools in modern medicine. Nowadays, their medical or health …