Despite the increasing use and success of interventional coronary reperfusion strategies,
morbidity and mortality from acute myocardial infarction are still substantial. Myocardial …

Acute myocardial infarction is caused by a sudden coronary artery occlusion and leads to
ischemia in the corresponding myocardial territory which generally results in myocardial …

Ischemia-reperfusion (IR) injury is central to the pathology of major cardiovascular diseases,
such as stroke and myocardial infarction. IR injury is mediated by several factors including …

The potential for ischemic preconditioning to reduce infarct size was first recognized more
than 30 years ago [180]. Despite extension of the concept to ischemic postcondition‑ing …

Acute myocardial infarction (AMI) and the heart failure (HF) that often follows are among the
leading causes of death and disability worldwide. As such, new treatments are needed to …

The incidence of ST segment elevation myocardial infarction (STEMI) has decreased over
the last two decades in developed countries, but mortality from STEMI despite widespread …

The damage inflicted on the myocardium during acute myocardial infarction is the result of 2
processes: ischemia and subsequent reperfusion (ischemia/reperfusion injury). During the …

Reperfusion is mandatory to salvage ischemic myocardium from infarction, but reperfusion
per se contributes to injury and ultimate infarct size. Therefore, cardioprotection beyond that …

The 30-year anniversary of the discovery of'ischaemic preconditioning'is in 2016. This
endogenous phenomenon can paradoxically protect the heart from acute myocardial …

Acute myocardial infarction (MI) is a major cause of death and disability worldwide. In
patients with MI, the treatment of choice for reducing acute myocardial ischemic injury and …