Stem cells are considered the fundamental underpinnings of tissue biology. The stem cell
microenvironment provides factors and elements that play significant roles in controlling the …

Hematopoietic stem cells (HSCs) are the life-long source of all types of blood cells. Their
function is controlled by their direct microenvironment, the HSC niche in the bone marrow …

Electrospinning provides a versatile and cost-effective route for the generation of continuous
nanofibres with high surface area-to-volume ratio from various polymers. In parallel, block …

Hematopoietic stem cells (HSCs) are adult multipotential stem cells with the capacity to
differentiate into all blood cells and immune cells, which are essential for maintaining …

Hematopoietic stem cells (HSCs) have proven their clinical relevance in stem cell
transplantation to cure patients with hematological disorders. Key to their regenerative …

Haematopoietic stem cells are the basis for building and maintaining lifelong
haematopoietic mechanisms and an important resource for the treatment of blood disorders …

Limited numbers of available hematopoietic stem cells (HSCs) limit the widespread use of
HSC-based therapies. Expansion systems for functional heterogenous HSCs remain to be …

Hematopoietic stem and progenitor cell (HSPC) research will help elucidate the
pathogenesis of hematologic diseases. The present study aimed to establish an isolation …

Recent advances in genetic engineering technology and stem cell biology have spurred
great interest in developing gene therapies for hereditary, as well as acquired hematological …

Bromodomain-containing proteins are known readers of histone acetylation that regulate
chromatin structure and transcription. Although the functions of bromodomain-containing …