Cytokines and chemokines in periodontitis

DE Ramadan, N Hariyani, R Indrawati… - European journal of …, 2020 - thieme-connect.com
The periodontium is the whole collagenous apparatus surrounding the tooth structure. It is
necessary to keep the tooth fixed to the underlying alveolar bone and sustained in its place …

Inflammatory profile of chronic apical periodontitis: a literature review

PH Braz-Silva, ML Bergamini… - Acta Odontologica …, 2019 - Taylor & Francis
Apical periodontitis caused by root canal infection is the most frequent pathological lesion in
the jaws, mainly manifested as periapical granulomas and cysts. Understanding of the …

Progranulin inhibits LPS-induced macrophage M1 polarization via NF-кB and MAPK pathways

L Liu, H Guo, A Song, J Huang, Y Zhang, S Jin, S Li… - BMC immunology, 2020 - Springer
Background Macrophage M1 polarization plays a pivotal role in inflammatory diseases.
Progranulin (PGRN) has potential anti-inflammation action, however, the effect of PGRN on …

Curcumin: An effective inhibitor of interleukin-6

M Ghandadi, A Sahebkar - Current pharmaceutical design, 2017 - ingentaconnect.com
Curcumin is apolyphenolic cominflammatory effects of curcumin. Moreover, curcumin can be
considered as potential therapy against IL-6 involvepound found in the dietary spice …

Five-year results of vital pulp therapy in permanent molars with irreversible pulpitis: a non-inferiority multicenter randomized clinical trial

S Asgary, MJ Eghbal, M Fazlyab, AA Baghban… - Clinical oral …, 2015 - Springer
Objectives Previous reported results of up to 12 months as well as 24-month follow-ups
revealed superior and equivalent treatment outcomes for vital pulp therapy (VPT) using …

An evidence-based systematic review of human knee post-traumatic osteoarthritis (PTOA): timeline of clinical presentation and disease markers, comparison of knee …

CM Khella, R Asgarian, JM Horvath, B Rolauffs… - International Journal of …, 2021 - mdpi.com
Understanding the causality of the post-traumatic osteoarthritis (PTOA) disease process of
the knee joint is important for diagnosing early disease and developing new and effective …

Central regulatory role of cytokines in periodontitis and targeting options

G Plemmenos, E Evangeliou… - Current medicinal …, 2021 - ingentaconnect.com
Background: Periodontitis is an immune-inflammatory disease that leads to the progressive
destruction of bone and connective tissue in the periodontal area. The cytokine network …

Role of Enterococcus faecalis in refractory apical periodontitis: from pathogenicity to host cell response

Z Deng, B Lin, F Liu, W Zhao - Journal of oral microbiology, 2023 - Taylor & Francis
Background: Refractory apical periodontitis (RAP) is an oral infectious disease
characterised by persistent inflammation, progressive alveolar bone destruction, and …

Cytokines in gingivitis and periodontitis: from pathogenesis to therapeutic targets

N Neurath, M Kesting - Frontiers in Immunology, 2024 - frontiersin.org
Chronic inflammatory processes in the oral mucosa and periodontitis are common disorders
caused by microflora and microbial biofilms. These factors activate both the innate and …

Synthetic high-density lipoprotein (sHDL): a bioinspired nanotherapeutics for managing periapical bone inflammation

R Dal-Fabbro, M Yu, L Mei, H Sasaki… - International Journal of …, 2024 - nature.com
Apical periodontitis (AP) is a dental-driven condition caused by pathogens and their toxins
infecting the inner portion of the tooth (ie., dental pulp tissue), resulting in inflammation and …