Safety of the fungal workhorses of industrial biotechnology: update on the mycotoxin and secondary metabolite potential of Aspergillus niger, Aspergillus oryzae, and …

JC Frisvad, LLH Møller, TO Larsen, R Kumar… - Applied Microbiology …, 2018 - Springer
This review presents an update on the current knowledge of the secondary metabolite
potential of the major fungal species used in industrial biotechnology, ie, Aspergillus niger …

Functional Genomics of Aspergillus oryzae: Strategies and Progress

B He, Y Tu, C Jiang, Z Zhang, Y Li, B Zeng - Microorganisms, 2019 - mdpi.com
Aspergillus oryzae has been used for the production of traditional fermentation and has
promising potential to produce primary and secondary metabolites. Due to the tough cell …

MIDDAS-M: Motif-Independent De Novo Detection of Secondary Metabolite Gene Clusters through the Integration of Genome Sequencing and Transcriptome Data

M Umemura, H Koike, N Nagano, T Ishii, J Kawano… - PloS one, 2013 - journals.plos.org
Many bioactive natural products are produced as “secondary metabolites” by plants,
bacteria, and fungi. During the middle of the 20th century, several secondary metabolites …

Phylogenomic evolutionary surveys of subtilase superfamily genes in fungi

J Li, F Gu, R Wu, JK Yang, KQ Zhang - Scientific reports, 2017 - nature.com
Subtilases belong to a superfamily of serine proteases which are ubiquitous in fungi and are
suspected to have developed distinct functional properties to help fungi adapt to different …

The postbiotic potential of Aspergillus oryzae – a narrative review

Y Seidler, G Rimbach, K Lüersen, G Vinderola… - Frontiers in …, 2024 - frontiersin.org
The filamentous fungus Aspergillus oryzae has a long tradition in East Asian food
processing. It is therefore not surprising that in recent years fermentation products of A …

Evolution of Aspergillus oryzae before and after domestication inferred by large-scale comparative genomic analysis

N Watarai, N Yamamoto, K Sawada, T Yamada - DNA Research, 2019 - academic.oup.com
Aspergillus oryzae is an industrially useful species, of which various strains have been
identified; however, their genetic relationships remain unclear. A. oryzae was previously …

Molecular analysis of S-morphology aflatoxin producers from the United States reveals previously unknown diversity and two new taxa

P Singh, KA Callicott, MJ Orbach, PJ Cotty - Frontiers in microbiology, 2020 - frontiersin.org
Aflatoxins are highly toxic carcinogens that detrimentally influence profitability of agriculture
and the health of humans and domestic animals. Several phylogenetically distinct fungi …

Genomic and transcriptomic comparison of Aspergillus oryzae strains: a case study in soy sauce koji fermentation

Y Zhong, X Lu, L Xing, SWA Ho… - Journal of Industrial …, 2018 - academic.oup.com
The filamentous fungus Aspergillus oryzae is used in soy sauce koji making due to its high
productivity of hydrolytic enzymes. In this study, we compared the genomes and …

Transcriptomic analysis reveals Aspergillus oryzae responds to temperature stress by regulating sugar metabolism and lipid metabolism

C Jiang, J Ge, B He, Z Zhang, Z Hu, Y Li, B Zeng - Plos one, 2022 - journals.plos.org
Aspergillus oryzae is widely used in industrial applications, which always encounter
changes within multiple environmental conditions during fermentation, such as temperature …

Motif-Independent Prediction of a Secondary Metabolism Gene Cluster Using Comparative Genomics: Application to Sequenced Genomes of Aspergillus and Ten …

I Takeda, M Umemura, H Koike, K Asai… - DNA …, 2014 - academic.oup.com
Despite their biological importance, a significant number of genes for secondary metabolite
biosynthesis (SMB) remain undetected due largely to the fact that they are highly diverse …